MARE-Marine and Environmental Sciences Centre & ARNET-Aquatic Research Infrastructure Network Associated Laboratory, ESTM, Polytechnic of Leiria, 2520-641 Peniche, Portugal.
Mar Drugs. 2023 Sep 28;21(10):515. doi: 10.3390/md21100515.
Algae have emerged as fascinating subjects of study due to their vast potential as sources of valuable metabolites with diverse biotechnological applications, including their use as fertilizers, feed, food, and even pharmaceutical precursors. Among the numerous compounds found in algae, lectins have garnered special attention for their unique structures and carbohydrate specificities, distinguishing them from lectins derived from other sources. Here, a comprehensive overview of the latest scientific and technological advancements in the realm of algal lectins with a particular focus on their antiviral properties is provided. These lectins have displayed remarkable effectiveness against a wide range of viruses, thereby holding great promise for various antiviral applications. It is worth noting that several alga species have already been successfully commercialized for their antiviral potential. However, the discovery of a diverse array of lectins with potent antiviral capabilities suggests that the field holds immense untapped potential for further expansion. In conclusion, algae stand as a valuable and versatile resource, and their lectins offer an exciting avenue for developing novel antiviral agents, which may lead to the development of cutting-edge antiviral therapies.
藻类由于其作为有价值代谢物的丰富来源的巨大潜力而成为引人关注的研究对象,这些代谢物具有多种生物技术应用,包括用作肥料、饲料、食品,甚至是药物前体。在藻类中发现的众多化合物中,凝集素因其独特的结构和碳水化合物特异性而受到特别关注,这使它们有别于其他来源的凝集素。在这里,提供了藻类凝集素领域最新科学和技术进展的全面概述,特别关注它们的抗病毒特性。这些凝集素对多种病毒表现出显著的有效性,因此在各种抗病毒应用中具有很大的潜力。值得注意的是,已经有几种藻类物种因其抗病毒潜力而成功商业化。然而,发现具有强大抗病毒能力的各种凝集素表明,该领域具有巨大的未开发潜力,可以进一步扩展。总之,藻类是一种有价值且用途广泛的资源,其凝集素为开发新型抗病毒药物提供了令人兴奋的途径,这可能会导致开发出前沿的抗病毒疗法。