Prananda Arya Tjipta, Dalimunthe Aminah, Harahap Urip, Simanjuntak Yogi, Peronika Epina, Karosekali Natasya Elsa, Hasibuan Poppy Anjelisa Zaitun, Syahputra Rony Abdi, Situmorang Putri Cahaya, Nurkolis Fahrul
Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.
Front Pharmacol. 2023 Oct 26;14:1288618. doi: 10.3389/fphar.2023.1288618. eCollection 2023.
Linn, a prominent member of the euphorbiaceae family, exhibits extensive distribution across a multitude of tropical and subtropical nations. Referred to as "Balakka" in Indonesia, this plant assumes various names across regions, such as "kimalaka," "balakka," "metengo," "malaka," and "kemloko" in North Sumatra, Ternate, Sundanese, and Java respectively. thrives in tropical locales like Indonesia, Malaysia, and Thailand, while also making its presence felt in subtropical regions like India, China, Uzbekistan, and Sri Lanka. The fruits of Balakka are enriched with bioactive constituents recognized for their wide-ranging benefits, including antioxidant, anti-aging, anti-cholesterol, anti-diabetic, immunomodulatory, antipyretic, analgesic, anti-inflammatory, chemoprotective, hepatoprotective, cardioprotective, antimutagenic, and antimicrobial properties. Comprising a spectrum of phenolic compounds (such as tannins, phenolic acids, and flavonoids), alkaloids, phytosterols, terpenoids, organic acids, amino acids, and vitamins, the bioactive components of Malacca fruit offer a diverse array of health-promoting attributes. In light of these insights, this review aims to comprehensively examine the pharmacological activities associated with and delve into the intricate composition of its phytochemical constituents.
林恩是大戟科的重要成员,在众多热带和亚热带国家广泛分布。在印度尼西亚被称为“巴拉卡”,这种植物在不同地区有不同的名称,例如在北苏门答腊、特尔纳特、巽他族和爪哇分别被称为“基马拉卡”、“巴拉卡”、“梅滕戈”、“马拉卡”和“凯姆洛科”。它生长在印度尼西亚、马来西亚和泰国等热带地区,同时在印度、中国、乌兹别克斯坦和斯里兰卡等亚热带地区也有分布。巴拉卡的果实富含生物活性成分,这些成分因其广泛的益处而闻名,包括抗氧化、抗衰老、抗胆固醇、抗糖尿病、免疫调节、解热、镇痛、抗炎、化学保护、肝脏保护、心脏保护、抗诱变和抗菌特性。马六甲果实的生物活性成分包括一系列酚类化合物(如单宁、酚酸和黄酮类化合物)、生物碱、植物甾醇、萜类化合物、有机酸、氨基酸和维生素,具有多种促进健康的特性。鉴于这些见解,本综述旨在全面研究与巴拉卡相关的药理活性,并深入探讨其植物化学成分的复杂组成。