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纤维肌痛症治疗中,纤维肌痛症严重程度类别及症状能否区分持续、间歇性和非阿片类药物使用者?

Do FIQR Severity Categories and Symptoms, Differentiate Between Continuous, Intermittent and Non-Opioid Users in the Treatment of Fibromyalgia?

作者信息

Pfalzgraf Andrea R, Friend Ronald, Jones Kimberly Dupree

机构信息

From the National University of Natural Medicine, Helfgott Research Institute, Portland, OR.

Department of Psychology, College of Arts and Sciences, Stony Brook University, Stony Brook, NY (emeritus); Fibromyalgia Research Unit, Oregon Health & Science University, Portland, OR.

出版信息

Pain Manag Nurs. 2024 Apr;25(2):181-188. doi: 10.1016/j.pmn.2023.10.005. Epub 2023 Nov 22.

Abstract

BACKGROUND

Many fibromyalgia patients utilize opioids to treat symptoms. It is important to better understand nuances regarding this treatment option and any stigma associated with this treatment modality.

AIM

This study: (1) assessed the prevalence of opioid use among continuous, intermittent, and non-opioid users in fibromyalgia patients; (2) determined whether the Revised Fibromyalgia Impact Questionnaire (FIQR) was useful in distinguishing opioid use and symptom burden; and (3) assessed whether fibromyalgia patients encountered stigma and/or invalidation.

DESIGN

A cross-sectional, observational study of 1,105 participants' responses to validated fibromyalgia and invalidation scales and demographic questions.

METHODS

The study employed online survey methodology.

RESULTS

A total of 45% of patients reported utilizing opioids (27% continuous, 18% intermittent, 55% non-users). FIQR disease categories (mild to most severe) strongly distinguished between opioid and non-opioid users with 59% of users falling in the most severe category and 68% of non-users falling in mild disease category (p < .0001). Interestingly, intermittent users were similar to non-users on FIQR severity (65.9 versus 65.7; p <0.60, 0-100) while continuous users reported greater severity than the former (73.9, p < .0001). Continuous users particularly reported more problems with daily activities (p < .0001), being overwhelmed (p < .0001), and being unable to accomplish goals (p < .0001). Stigma related to being 'drug seeking' and being 'judged'. Invalidation was infrequent.

CONCLUSIONS

Opioid use is common in fibromyalgia and increases monotonically with FIQR severity. Multidisciplinary approaches which help patients perform daily activities, decrease feelings of overwhelm, accomplish goals, and reduce stigma may be beneficial.

摘要

背景

许多纤维肌痛患者使用阿片类药物来治疗症状。更好地了解这种治疗选择的细微差别以及与这种治疗方式相关的任何污名化现象很重要。

目的

本研究:(1)评估纤维肌痛患者中持续、间歇和非阿片类药物使用者的阿片类药物使用 prevalence;(2)确定修订后的纤维肌痛影响问卷(FIQR)是否有助于区分阿片类药物使用和症状负担;(3)评估纤维肌痛患者是否遭遇污名化和/或被否定。

设计

一项横断面观察性研究,对1105名参与者对经过验证的纤维肌痛和被否定量表以及人口统计学问题的回答进行研究。

方法

本研究采用在线调查方法。

结果

共有45%的患者报告使用阿片类药物(27%为持续使用者,18%为间歇使用者,55%为非使用者)。FIQR疾病类别(从轻度到最严重)在阿片类药物使用者和非使用者之间有显著区分,59%的使用者属于最严重类别,68%的非使用者属于轻度疾病类别(p <.0001)。有趣的是,间歇使用者在FIQR严重程度上与非使用者相似(65.9对65.7;p <0.60,0 - 100),而持续使用者报告的严重程度高于前者(73.9,p <.0001)。持续使用者尤其报告在日常活动方面有更多问题(p <.)。与“寻求药物”和“被评判”相关的污名化现象。被否定的情况不常见。

结论

阿片类药物在纤维肌痛中使用很常见,并且随着FIQR严重程度单调增加。有助于患者进行日常活动、减少不知所措的感觉、实现目标并减少污名化的多学科方法可能有益。

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