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牙龈卟啉单胞菌和真杆菌引起的脑脓肿模拟急性脑卒中。

Brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum mimicking acute stroke.

机构信息

Clinical Microbiology Service, Laredo Regional Hospital, Av. Derechos Humanos, 40, 39770, Laredo, Cantabria, Spain.

Clinical Microbiology Service, Basurto University Hospital, 18 Avenida Montevideo, 48013, Bilbao, Biscay, Spain; Biocruces Bizkaia Health Research Institute, Cruces Plaza, 48903, Biscay, Spain.

出版信息

Anaerobe. 2023 Dec;84:102801. doi: 10.1016/j.anaerobe.2023.102801. Epub 2023 Nov 23.

Abstract

We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 weeks of antibiotic with good clinical and radiological evolution.

摘要

我们描述了一例由牙龈卟啉单胞菌和真杆菌引起的 65 岁男性脑脓肿病例。该患者在检查时表现为右侧中央面神经瘫痪、缄默和右侧偏瘫。患者接受了左额开颅术以清除脑脓肿。采集标本进行微生物分析,并开始静脉注射左乙拉西坦、地塞米松、美罗培南(1 g/8 h)和利奈唑胺(600 mg/12 h)。在鉴定出厌氧菌后,抗生素治疗改为哌拉西林/他唑巴坦(4 g/0.5 g/8 h),完成 8 周的抗生素治疗,临床和影像学均有良好的改善。

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