Clinical Microbiology Service, Laredo Regional Hospital, Av. Derechos Humanos, 40, 39770, Laredo, Cantabria, Spain.
Clinical Microbiology Service, Basurto University Hospital, 18 Avenida Montevideo, 48013, Bilbao, Biscay, Spain; Biocruces Bizkaia Health Research Institute, Cruces Plaza, 48903, Biscay, Spain.
Anaerobe. 2023 Dec;84:102801. doi: 10.1016/j.anaerobe.2023.102801. Epub 2023 Nov 23.
We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 weeks of antibiotic with good clinical and radiological evolution.
我们描述了一例由牙龈卟啉单胞菌和真杆菌引起的 65 岁男性脑脓肿病例。该患者在检查时表现为右侧中央面神经瘫痪、缄默和右侧偏瘫。患者接受了左额开颅术以清除脑脓肿。采集标本进行微生物分析,并开始静脉注射左乙拉西坦、地塞米松、美罗培南(1 g/8 h)和利奈唑胺(600 mg/12 h)。在鉴定出厌氧菌后,抗生素治疗改为哌拉西林/他唑巴坦(4 g/0.5 g/8 h),完成 8 周的抗生素治疗,临床和影像学均有良好的改善。