Huyghe Eric, Faix Antoine, Bouker Amin, Methorst Charlotte
Département d'urologie, hôpital de Rangueil, CHU de Toulouse, Toulouse, France; Service de médecine de la reproduction, hôpital Paule-de-Viguier, CHU de Toulouse, Toulouse, France; UMR DEFE, Inserm 1203, université de Toulouse, université de Montpellier, Montpellier, France.
Clinique Saint-Roch, 560, avenue du colonel Pavelet-dit-Villars, 34000 Montpellier, France.
Prog Urol. 2023 Nov;33(13):697-709. doi: 10.1016/j.purol.2023.09.007.
Testicular and epididymal sperm extraction surgery is a frequent procedure. However, to date, there has been no French consensus on the technique to be preferred in the various situations of male infertility and on the best way to perform them. We therefore decided to proceed with a formalized expert consensus, using the method recommended by the French National Authority for Health. The aim was to provide the French urology community with practical advice on how best to perform these procedures.
Twenty-six international experts met online for the consensus. A research committee carried out a comprehensive literature review and prepared the 55 statements submitted to the rating group. After 2 rounds of scoring, 50 recommendations were validated in March 2023, having achieved a consensus of more than 85% among the experts.
The consensus covered (1) preparation for sperm extraction surgery, (2) the different sperm extraction surgery techniques (Microsurgical epididymal sperm aspiration [MESA], Percutaneous epididymal sperm aspiration [PESA], Conventional Testicular Sperm Extraction [TESE], Microsurgical Testicular Sperm Extraction [micro-TESE]), (3) advice to be given to the patient concerning the postoperative period, before presenting the results of the sperm extraction surgeries.
The expert consensus meeting on the performance of sperm extraction surgery presented a set of clinical guidelines based on the available literature and expert opinion. These guidelines should have a favourable effect on the development of this activity in France.
睾丸和附睾精子提取手术是一种常见的手术。然而,迄今为止,法国在男性不育的各种情况下应首选的技术以及实施这些技术的最佳方法上尚未达成共识。因此,我们决定采用法国国家卫生管理局推荐的方法进行正式的专家共识。目的是为法国泌尿外科界提供关于如何最好地实施这些手术的实用建议。
26名国际专家在线召开共识会议。一个研究委员会进行了全面的文献综述,并准备了提交给评分小组的55份声明。经过两轮评分,50条建议于2023年3月得到验证,专家们达成了超过85%的共识。
共识涵盖了(1)精子提取手术的准备工作,(2)不同的精子提取手术技术(显微外科附睾精子抽吸术[MESA]、经皮附睾精子抽吸术[PESA]、传统睾丸精子提取术[TESE]、显微外科睾丸精子提取术[micro-TESE]),(3)在公布精子提取手术结果之前,就术后阶段向患者提供的建议。
精子提取手术实施的专家共识会议基于现有文献和专家意见提出了一套临床指南。这些指南应该会对法国这项业务的发展产生积极影响。