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经软性输尿管镜治疗同侧上尿路结石清除术后,输尿管结石体积大和女性性别可预测围手术期并发症。

Ureteral stone volume and female gender predicts perioperative complications after complete ipsilateral upper urinary tract stone removal using flexible ureterorenoscopy.

机构信息

Department of Urology, Ohguchi East General Hospital, 2-19-1 Irie, Kanagawa-Ku, Yokohama, Kanagawa, 221-0014, Japan.

Department of Urology, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-Ku, Yokohama, Kanagawa, 236-0004, Japan.

出版信息

Int Urol Nephrol. 2024 May;56(5):1611-1616. doi: 10.1007/s11255-023-03899-1. Epub 2023 Dec 20.

Abstract

PURPOSE

To identify the risk factors for perioperative complications to prevent perioperative complications after complete ipsilateral upper urinary stone removal using flexible ureterorenoscopy.

MATERIALS AND METHODS

We retrospectively examined 111 patients who underwent flexible ureterorenoscopy for ipsilateral renal stones with a diameter ≥ 5 mm at the same time as ureterorenoscopy for ureteric stones. The flexible ureterorenoscopy procedures were performed following the fragmentation technique. Patients who experienced (complication group) and did not experience (non-complication group) perioperative complications were compared. The complication group included 33 patients with Clavien-Dindo classification scores of I, II, III, or IV and/or those with a body temperature of > 37.5 ℃ during hospitalization.

RESULTS

The overall stone volume, stone-free rate and procedure duration were 1.71 mL, 96.4% and 77 min, respectively. The rate of perioperative complications was 29.7% (grade 1, 2 and 3 was 23.4%, 5.4% and 0.9%, respectively). Severe complications (Clavien-Dindo grade 4) were not observed. Multivariable analysis revealed that ureteral stone volume and female patients were independent predictors of perioperative complications after flexible ureterorenoscopy (p = 0.015 and 0.017, respectively).

CONCLUSIONS

This study showed that ureteral stone volume and female gender have the possibility to increase perioperative complications. These preliminary data help to select for patients who are at low risk of complications. Therefore, in these selected patients, complete ipsilateral upper urinary tract stone removal using flexible ureterorenoscopy may reduce the recurrence of urolithiasis without increasing perioperative complications.

摘要

目的

确定围手术期并发症的风险因素,以预防经软性输尿管镜碎石术同期治疗同侧上尿路结石的围手术期并发症。

材料与方法

我们回顾性分析了 111 例同期接受软性输尿管镜碎石术治疗输尿管结石和同侧肾结石(结石直径≥5mm)的患者。软性输尿管镜碎石术采用碎石技术。比较发生(并发症组)和未发生(非并发症组)围手术期并发症的患者。并发症组包括 33 例 Clavien-Dindo 分级 I、II、III 或 IV 级患者和/或住院期间体温>37.5℃的患者。

结果

总的结石体积、结石清除率和手术时间分别为 1.71mL、96.4%和 77min。围手术期并发症发生率为 29.7%(1 级、2 级和 3 级分别为 23.4%、5.4%和 0.9%)。未观察到严重并发症(Clavien-Dindo 分级 4 级)。多变量分析显示,输尿管结石体积和女性患者是软性输尿管镜碎石术后围手术期并发症的独立预测因素(p=0.015 和 0.017)。

结论

本研究表明,输尿管结石体积和女性性别可能增加围手术期并发症。这些初步数据有助于选择围手术期并发症风险较低的患者。因此,在这些选定的患者中,使用软性输尿管镜碎石术同期清除同侧上尿路结石可能会降低尿石症的复发率,而不会增加围手术期并发症。

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