Department of Gynecology and Obstetrics, University Hospital of Cologne, Medical Faculty, Cologne, Germany.
Department of Gynecology and Obstetrics, University Hospital of Cologne, Medical Faculty, Cologne, Germany
In Vivo. 2024 Jan-Feb;38(1):299-307. doi: 10.21873/invivo.13439.
BACKGROUND/AIM: Due to still controversial discussion regarding appropriate termination of low-risk singleton pregnancies beyond term, this retrospective study aimed to evaluate maternal and perinatal outcomes depending on gestational age and obstetric management.
This is a retrospective cohort analysis including 3.242 low-risk singleton deliveries at the Department of Obstetrics of the University Hospital of Cologne between 2017 and 2022. According to current national guidelines, the cohort was subdivided into three gestational groups, group 1: 40+0-40+6 weeks, group 2: 40+7-40+10 weeks and group 3>40+10 weeks.
In our cohort, advanced gestational age was associated with higher rates of secondary caesarean sections, lower rates of spontaneous vaginal deliveries, higher rates of meconium-stained amniotic fluid and depressed neonates with APGAR < 7 after 5 min. Analyzing obstetric management, induction of labor significantly increased the rate of secondary sections and reduced the rate of spontaneous deliveries, while the percentage of assistant vaginal deliveries was independent from obstetric management and gestational age. Induction of labor also significantly enhanced the need for tocolytic subpartu and epidural anesthesia and caused higher rates of abnormalities in cardiotocography (CTG), which also resulted in more frequent fetal scalp blood testing; however, the rate of fetal acidosis was independent of both obstetric management and gestational age.
Our study supports expectant management of low-risk pregnancies beyond term, as induction of labor increased the rate of secondary sections and did not improve perinatal outcome.
背景/目的:由于对于超出预产期的低危单胎妊娠应如何适当终止,目前仍存在争议,因此本回顾性研究旨在评估根据孕龄和产科管理的不同,母婴围生期结局。
这是一项回顾性队列分析,纳入了科隆大学医院妇产科 2017 年至 2022 年间的 3242 例低危单胎分娩。根据当前的国家指南,将队列分为三个孕龄组:组 1:40+0-40+6 周;组 2:40+7-40+10 周;组 3:>40+10 周。
在本队列中,较高的孕龄与较高的继发性剖宫产率、较低的自然分娩率、较高的羊水胎粪污染率以及 APGAR<7 的新生儿比例降低相关。分析产科管理发现,引产显著增加了继发性剖宫产率,降低了自然分娩率,而助产分娩率与产科管理和孕龄无关。引产还显著增加了使用宫缩抑制剂和硬膜外麻醉的需求,并导致胎心监护(CTG)异常的发生率增加,这也导致更频繁地进行胎儿头皮血检测;然而,胎儿酸中毒的发生率与产科管理和孕龄均无关。
我们的研究支持对超出预产期的低危妊娠进行期待管理,因为引产增加了继发性剖宫产率,且并未改善围生期结局。