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评估药物治疗和支架置入术对慢性胰腺炎患者生活质量的影响:一项前瞻性研究。

Assessing the Impact of Medication and Stenting on the Quality of Life of Patients With Chronic Pancreatitis: A Prospective Study.

作者信息

Rajput Ravindrasingh, Prasad S Durga, Pai C Ganesh

机构信息

Physiology, American University of Antigua College of Medicine, St. John's, ATG.

Pharmacology, American University of Antigua College of Medicine, St. John's, ATG.

出版信息

Cureus. 2023 Dec 7;15(12):e50106. doi: 10.7759/cureus.50106. eCollection 2023 Dec.

Abstract

This research aimed to assess the effect of pharmacotherapy alone versus the combination of pharmacotherapy and endoscopic stenting on the quality of life (QoL) outcomes of chronic pancreatitis patients. Chronic pancreatitis, an inflammatory disease, often presents with persistent pain, affecting patients' quality of life. Thirty patients treated either with pharmacotherapy alone or with the addition of endoscopic stenting were analyzed. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) was used to gather data on the patients' QoL. Results showed that both treatment groups experienced improvements in global health, role functioning, fatigue, and abdominal pain scores over follow-ups. Specifically, the stenting group saw notable enhancements in global health and role functioning. The study's conclusions provide valuable insights into the potential benefits of both treatments, with stenting offering significant improvements in certain QoL parameters. However, the sample size and source limit generalizability, suggesting the need for more extensive research across diverse settings.

摘要

本研究旨在评估单纯药物治疗与药物治疗联合内镜支架置入术对慢性胰腺炎患者生活质量(QoL)结果的影响。慢性胰腺炎是一种炎症性疾病,常伴有持续性疼痛,影响患者的生活质量。对30例接受单纯药物治疗或加用内镜支架置入术治疗的患者进行了分析。使用欧洲癌症研究与治疗组织生活质量问卷(EORTC QLQ-C30)收集患者生活质量数据。结果显示,两个治疗组在随访期间的总体健康、角色功能、疲劳和腹痛评分均有所改善。具体而言,支架置入组在总体健康和角色功能方面有显著提高。该研究的结论为两种治疗方法的潜在益处提供了有价值的见解,支架置入术在某些生活质量参数方面有显著改善。然而,样本量和来源限制了研究结果的普遍性,这表明需要在不同环境中进行更广泛的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd9f/10771073/179594840078/cureus-0015-00000050106-i01.jpg

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