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临床实践中的生活方式正念

Lifestyle Mindfulness In Clinical Practice

作者信息

Srour Ranya A., Keyes Daniel

机构信息

Michigan State University College of Human Medicine

Michigan State University

Abstract

Mindfulness is a self-regulated state of non-judgemental and purposeful awareness of the present moment. Psychotherapy pioneer Jon Kabat-Zinn developed the mindfulness-based stress reduction (MBSR) protocol for the self-regulation of chronic pain and stress through meditation and mindfulness. In preliminary studies, Kabat-Zinn describes how meditation facilitates a state of detached observation by redirecting attention toward proprioception. This "uncouples" the sensory component of pain from the affective or emotional element, thus reducing suffering through cognitive reappraisal. Individuals can reinterpret and reframe their thoughts through cognitive reappraisal, reducing stress and suffering. Studies report strong adherence and long-term positive effects of MBSR on stress, depression, anxiety, and pain following the training period, with benefits lasting for several years. A pivotal study on mindfulness and the brain demonstrated that a brief MBSR program increased left-sided anterior activity correlated with positive affect.  More recent research further supports this finding, indicating that mindfulness meditation reduces stress and enhances the activation of brain regions linked to mood regulation and attention control. Specifically, it is suggested that MBSR improves the activation of the brain's anterior cingulate cortex, an executive attention center. These findings highlight how mindfulness strengthens neuronal networks, cultivating self-awareness, emotional regulation, and adaptive stress responses. Furthermore, mindfulness may strengthen the mind-body connection, enabling individuals to effectively self-regulate symptoms of pain, anxiety, depression, and stress. Mindfulness aims to liberate the self from physical and psychological suffering while cultivating the necessary skills to manage stressful situations. It is emphasized that mindfulness is not a quick fix but a long-term intervention that requires dedicated practice and an intentional way of living. Stress is a fundamental and necessary part of life. Stress is not exclusive to negative experiences and may result from any form of stimulation, including positive experiences. Cortisol, the stress hormone, is produced during negative and positive experiences and is crucial in promoting alertness, focus, and energy. It allows us to get up in the morning and maintain energy throughout the day. However, prolonged or excessive stress can have detrimental effects on our health. High cortisol levels over an extended period can disrupt sleep patterns, impair cognitive function, weaken the immune system, and contribute to various health problems. Therefore, while stress is essential in moderate amounts, it is crucial to manage excessive stress to maintain a healthy lifestyle. The body's response to stressors can be observed through physiological and behavioral changes controlled by biological processes. Recent research supports the theory that the hypothalamic-pituitary-adrenal (HPA) axis regulates the stress response. Activation of the HPA axis begins through an initial exposure to a stressor. The activation of the HPA axis has neuronal origins regulated by the paraventricular nucleus of the hippocampus, which releases corticotropin-releasing factors. The HPA axis then releases glucocorticoids, stimulating the body's physical response to stress.  Glucocorticoids and other cortical hormones are major regulators of the HPA axis and normally produce a healthy, adaptive stress response. However, chronic stress results in excessive or prolonged activation of the HPA axis, leading to dysregulation and a maladaptive stress response. A wide body of evidence supports using a mind-body approach to regulate the HPA axis and address psychophysiological stress. Non-pharmacological behavioral interventions like MBSR have been shown to effectively regulate exaggerated or problematic stress responses through breathing exercises, meditation, and mindfulness (see . MSBR and Stress). Behavioral interventions like MBSR aim not to remove stress but to manage it effectively and completely.

摘要

正念是一种自我调节的状态,即对当下时刻进行无评判且有目的的觉察。心理治疗先驱乔恩·卡巴金开发了基于正念的减压疗法(MBSR),通过冥想和正念来自我调节慢性疼痛和压力。在初步研究中,卡巴金描述了冥想如何通过将注意力重新导向本体感觉来促进一种超脱观察的状态。这将疼痛的感觉成分与情感或情绪元素“分离”,从而通过认知重新评估减轻痛苦。个体可以通过认知重新评估重新诠释和重构自己的想法,减轻压力和痛苦。研究报告称,在训练期之后,MBSR对压力、抑郁、焦虑和疼痛有很强的依从性和长期积极影响,且益处可持续数年。一项关于正念与大脑的关键研究表明,一个简短的MBSR项目增加了与积极情绪相关的左侧前部活动。最近的研究进一步支持了这一发现,表明正念冥想可以减轻压力,并增强与情绪调节和注意力控制相关的脑区的激活。具体而言,有人认为MBSR改善了大脑前扣带回皮质(一个执行注意力中心)的激活。这些发现凸显了正念如何强化神经网络,培养自我意识、情绪调节和适应性应激反应。此外,正念可能会加强身心联系,使个体能够有效地自我调节疼痛、焦虑、抑郁和压力症状。正念旨在将自我从身心痛苦中解放出来,同时培养应对压力情境所需的技能。需要强调的是,正念不是一种快速解决方案,而是一种长期干预措施,需要专门的练习和一种有意识的生活方式。压力是生活中基本且必要的一部分。压力并非仅存在于负面经历中,任何形式的刺激,包括积极经历,都可能导致压力。皮质醇,即应激激素,在负面和正面经历中都会产生,对促进警觉性、专注力和能量至关重要。它使我们能够早上起床并一整天保持精力充沛。然而,长期或过度的压力会对我们的健康产生有害影响。长时间高皮质醇水平会扰乱睡眠模式、损害认知功能、削弱免疫系统,并导致各种健康问题。因此,虽然适度的压力是必不可少的,但管理过度的压力对于维持健康的生活方式至关重要。身体对应激源的反应可以通过由生物过程控制的生理和行为变化来观察。最近的研究支持下丘脑 - 垂体 - 肾上腺(HPA)轴调节应激反应的理论。HPA轴的激活始于最初接触应激源。HPA轴的激活具有神经元起源,受海马旁室核调节,该核会释放促肾上腺皮质激素释放因子。然后HPA轴释放糖皮质激素,刺激身体对应激的生理反应。糖皮质激素和其他皮质激素是HPA轴的主要调节因子,通常会产生健康的适应性应激反应。然而,慢性压力会导致HPA轴过度或长期激活,从而导致失调和适应不良的应激反应。大量证据支持采用身心方法来调节HPA轴并应对心理生理压力。像MBSR这样的非药物行为干预已被证明可以通过呼吸练习、冥想和正念有效地调节过度或有问题的应激反应(见.MSBR与压力)。像MBSR这样的行为干预旨在不是消除压力,而是有效地全面管理压力。

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