Suhag Alisha, Webb Thomas L, Holmes John
Healthy Lifespan Institute, School of Health and Related Research, University of Sheffield, Sheffield, United Kingdom.
Department of Psychology, University of Sheffield, Sheffield, United Kingdom.
PLoS One. 2024 Jan 25;19(1):e0297422. doi: 10.1371/journal.pone.0297422. eCollection 2024.
Health-risk behaviours such as smoking, unhealthy nutrition, alcohol consumption, and physical inactivity (termed SNAP behaviours) are leading risk factors for multimorbidity and tend to cluster (i.e. occur in specific combinations within distinct subpopulations). However, little is known about how these clusters change with age in older adults, and whether and how cluster membership is associated with multimorbidity.
Repeated measures latent class analysis using data from Waves 4-8 of the English Longitudinal Study of Ageing (ELSA; n = 4759) identified clusters of respondents with common patterns of SNAP behaviours over time. Disease status (from Wave 9) was used to assess disorders of eight body systems, multimorbidity, and complex multimorbidity. Multinomial and binomial logistic regressions were used to examine how clusters were associated with socio-demographic characteristics and disease status.
Seven clusters were identified: Low-risk (13.4%), Low-risk yet inactive (16.8%), Low-risk yet heavy drinkers (11.4%), Abstainer yet inactive (20.0%), Poor diet and inactive (12.9%), Inactive, heavy drinkers (14.5%), and High-risk smokers (10.9%). There was little evidence that these clusters changed with age. People in the clusters characterised by physical inactivity (in combination with other risky behaviours) had lower levels of education and wealth. People in the heavy drinking clusters were predominantly male. Compared to other clusters, people in the Low-risk and Low-risk yet heavy drinkers had a lower prevalence of all health conditions studied. In contrast, the Abstainer but inactive cluster comprised mostly women and had the highest prevalence of multimorbidity, complex multimorbidity, and endocrine disorders. High-risk smokers were most likely to have respiratory disorders.
Health-risk behaviours tend to be stable as people age and so ought to be addressed early. We identified seven clusters of older adults with distinct patterns of behaviour, socio-demographic characteristics and multimorbidity prevalence. Intervention developers could use this information to identify high-risk subpopulations and tailor interventions to their behaviour patterns and socio-demographic profiles.
吸烟、不健康饮食、饮酒及缺乏身体活动等健康风险行为(简称SNAP行为)是导致多种疾病的主要风险因素,且往往会聚集在一起(即在不同亚人群中以特定组合出现)。然而,对于这些聚集模式在老年人中如何随年龄变化,以及聚集成员身份是否与多种疾病相关及如何相关,我们知之甚少。
利用英国老年纵向研究(ELSA)第4 - 8轮的数据进行重复测量潜在类别分析,以确定随着时间推移具有共同SNAP行为模式的受访者群体。采用第9轮的疾病状况评估八个身体系统的疾病、多种疾病及复杂的多种疾病。使用多项和二项逻辑回归来研究这些群体与社会人口学特征及疾病状况之间的关联。
确定了七个群体:低风险组(13.4%)、低风险但不活动组(16.8%)、低风险但酗酒组(11.4%)、戒酒但不活动组(20.0%)、饮食不良且不活动组(12.9%)、不活动且酗酒组(14.5%)和高风险吸烟者组(10.9%)。几乎没有证据表明这些群体随年龄变化。以缺乏身体活动为特征(与其他风险行为相结合)的群体中的人教育程度和财富水平较低。酗酒群体中的人主要为男性。与其他群体相比,低风险组和低风险但酗酒组中研究的所有健康状况的患病率较低。相比之下,戒酒但不活动组主要由女性组成,且多种疾病、复杂的多种疾病及内分泌疾病的患病率最高。高风险吸烟者最有可能患有呼吸系统疾病。
随着人们年龄增长,健康风险行为往往较为稳定,因此应尽早加以应对。我们确定了七个老年人群体,他们具有不同的行为模式、社会人口学特征和多种疾病患病率。干预措施开发者可利用这些信息识别高风险亚人群,并根据其行为模式和社会人口学特征制定针对性干预措施。