Correa Ricardo Amorim, Arancibia Francisco, De Ávila Kfouri Renato, Chebabo Alberto, García Gabriel, Gutiérrez Robledo Luis Miguel, Lopardo Gustavo, Nemerovsky Julio, Pérez Carlos M, Rendon Adrian, Ruiz-Palacios Guillermo M, Aggarwal Bhumika, Berzanskis Arnas, Cintra Otavio
Medical School, Pulmonology and Thoracic Surgery Department, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Pulmonary Department, Instituto Nacional del Tórax and Clínica Santa María, Santiago de Chile, Chile.
Pulm Ther. 2024 Mar;10(1):1-20. doi: 10.1007/s41030-024-00253-3. Epub 2024 Feb 15.
Respiratory syncytial virus (RSV) is a significant global health concern and major cause of hospitalization, particularly among infants and older adults. The clinical impact of RSV is well characterized in infants; however, in many countries, the burden and risk of RSV in older populations are overlooked. In Latin America, there are limited data on RSV epidemiology and disease management in older adults. Therefore, the impact of RSV in this region needs to be addressed. Here, current insights on RSV infections in older populations in Latin America, including those with underlying health conditions, are discussed. We also outline the key challenges limiting our understanding of the burden of RSV in Latin America in a worldwide context and propose an expert consensus to improve our understanding of the burden of RSV in the region. By so doing, we aim to ultimately improve disease management and outcomes of those at risk and to alleviate the impact on healthcare systems.A graphical plain language summary is available with this article.
呼吸道合胞病毒(RSV)是一个重大的全球健康问题,也是住院治疗的主要原因,尤其是在婴儿和老年人中。RSV对婴儿的临床影响已得到充分描述;然而,在许多国家,老年人群中RSV的负担和风险被忽视了。在拉丁美洲,关于老年人RSV流行病学和疾病管理的数据有限。因此,需要解决RSV在该地区的影响。在此,我们讨论了拉丁美洲老年人群(包括有潜在健康状况的人群)中RSV感染的当前见解。我们还概述了在全球范围内限制我们对拉丁美洲RSV负担理解的关键挑战,并提出了一项专家共识,以增进我们对该地区RSV负担的理解。通过这样做,我们旨在最终改善高危人群的疾病管理和治疗结果,并减轻对医疗系统的影响。本文配有一份图形化的通俗易懂的总结。