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中国兰州空气污染与每日泌尿生殖系统疾病住院的短期关联。

Short-term association between air pollution and daily genitourinary disorder admissions in Lanzhou, China.

机构信息

School of Public Health, Lanzhou University, Lanzhou, 730000, People's Republic of China.

出版信息

Environ Geochem Health. 2024 Feb 17;46(3):74. doi: 10.1007/s10653-023-01821-3.

Abstract

The aim of this study was to determine the relationship between short-term exposure to ambient air pollution and the number of daily hospital admissions for genitourinary disorders in Lanzhou. Hospital admission data and air pollutants, including PM, PM, SO, NO, O8h and CO, were obtained from the period 2013 to 2020. A generalized additive model (GAM) combined with distribution lag nonlinear model (DLNM) based on quasi-Poisson distribution was used by the controlling for trends, weather, weekdays and holidays. Short-term exposure to PM, NO and CO increased the risk of genitourinary disorder admissions with RR of 1.0096 (95% CI 1.0002-1.0190), 1.0255 (95% CI 1.0123-1.0389) and 1.0686 (95% CI 1.0083-1.1326), respectively. PM, O8h and SO have no significant effect on genitourinary disorders. PM and NO are more strongly correlated in female and ≥ 65 years patients. CO is more strongly correlated in male and < 65 years patients. PM, NO and CO are risk factors for genitourinary morbidity, and public health interventions should be strengthened to protect vulnerable populations.

摘要

本研究旨在探讨兰州市短期暴露于大气污染与泌尿系统疾病日住院人数之间的关系。研究期间为 2013 年至 2020 年,收集了医院入院数据和大气污染物(包括 PM、PM、SO、NO、O8h 和 CO)数据。采用广义相加模型(GAM)结合基于泊松分布的分布滞后非线性模型(DLNM),控制趋势、天气、工作日和节假日等因素。结果表明,短期暴露于 PM、NO 和 CO 增加了泌尿系统疾病住院的风险,RR 分别为 1.0096(95%CI 1.0002-1.0190)、1.0255(95%CI 1.0123-1.0389)和 1.0686(95%CI 1.0083-1.1326)。PM、O8h 和 SO 对泌尿系统疾病无显著影响。PM 和 NO 在女性和≥65 岁患者中相关性更强,而 CO 在男性和<65 岁患者中相关性更强。PM、NO 和 CO 是泌尿系统疾病发病的危险因素,应加强公共卫生干预,保护弱势群体。

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