Alshehri Ali A, Albahli Odai M, Alturki Abdulrahman M, Alwasaidi Turki A, Alfaris Nasreen F
Endocrinology and Metabolism, Endocrine and Metabolism Center, King Fahad Medical City, Riyadh, SAU.
Family Medicine, Saudi Board of Family Medicine, Kingdom of Saudi Arabia Ministry of Health, Riyadh, SAU.
Cureus. 2024 Jan 17;16(1):e52424. doi: 10.7759/cureus.52424. eCollection 2024 Jan.
Background Saudi Arabia has a high prevalence of chronic diseases such as obesity. Moreover, iron deficiency anemia (IDA) in developing countries is the most prevalent type of anemia. This study aims to assess the correlation between anemia related to poor iron status and obesity. Methods A cross-sectional observational study was conducted at the obesity center in King Fahad Medical City, Saudi Arabia, from April to September 2020. Two hundred and forty participants were needed to be included in the study. The data was gathered by utilizing a designed data collection form. Socio-demographic data, weight and height, questions related to the history of anemia, and gynecological data (for females) were collected. The data was analyzed using SPSS (Statistical Package for Social Science) version 28.0. Descriptive statistics were used to present numerical and categorical data and a Chi-square test was conducted to assess the correlation between categorical variables. Informed written consent was obtained from all participants and ethical approval was obtained from the Ethical Board Committee in King Fahad Medical City. Results The study included 240 participants. Two-thirds of the study population are females (64.6%), 66.7% are married, and 65.8% have obesity. Almost one-half of the study population (46%, N=128) was diagnosed with IDA with malnourishment being the most common reason for IDA (88.2%). The results indicated a correlation between obesity and the prevalence of IDA. The prevalence of IDA among participants with obesity (60.4%) was significantly higher compared to non-obese participants (39.5%), p=0.002. The study found that females and underweight individuals have a higher prevalence of IDA (p<0.001). Conclusion Results of the present study suggest that obesity could be associated with a risk of IDA. In addition, Saudi women could be more prone to IDA than men. Further prospective controlled studies among diverse populations in Saudi Arabia including laboratory assessment of inflammatory markers and iron status are required to better understand the correlation between obesity and IDA.
沙特阿拉伯肥胖等慢性病的患病率很高。此外,发展中国家的缺铁性贫血(IDA)是最常见的贫血类型。本研究旨在评估与铁状态不佳相关的贫血与肥胖之间的相关性。方法:2020年4月至9月,在沙特阿拉伯法赫德国王医疗城的肥胖中心进行了一项横断面观察性研究。该研究需要纳入240名参与者。通过使用设计好的数据收集表收集数据。收集社会人口统计学数据、体重和身高、与贫血病史相关的问题以及(女性的)妇科数据。使用SPSS(社会科学统计软件包)28.0版对数据进行分析。描述性统计用于呈现数值和分类数据,并进行卡方检验以评估分类变量之间的相关性。所有参与者均获得了知情书面同意,并获得了法赫德国王医疗城伦理委员会的伦理批准。结果:该研究纳入了240名参与者。研究人群中有三分之二为女性(64.6%),66.7%已婚,65.8%患有肥胖症。几乎一半的研究人群(46%,N = 128)被诊断为缺铁性贫血,营养不良是缺铁性贫血最常见的原因(88.2%)。结果表明肥胖与缺铁性贫血的患病率之间存在相关性。肥胖参与者中铁缺铁性贫血的患病率(60.4%)显著高于非肥胖参与者(39.5%),p = 0.002。研究发现女性和体重过轻的个体缺铁性贫血的患病率更高(p < 0.001)。结论:本研究结果表明肥胖可能与缺铁性贫血风险相关。此外,沙特女性可能比男性更容易患缺铁性贫血。需要在沙特阿拉伯的不同人群中进行进一步的前瞻性对照研究,包括对炎症标志物和铁状态进行实验室评估,以更好地了解肥胖与缺铁性贫血之间的相关性。