School of Medicine, University of Eastern Finland, Kuopio, Finland.
Institute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland.
Pediatr Allergy Immunol. 2024 Mar;35(3):e14099. doi: 10.1111/pai.14099.
Several recent studies have investigated the association between maternal diet during pregnancy and wheezing or asthma in children. However, whether a specific dietary pattern during pregnancy protects children from wheezing or atopic diseases remains unclear. This study investigated the association between The Alternative Healthy Eating Index for Pregnancy (AHEI-P), the Dietary Inflammatory Index (DII), and the risk for wheezing and atopic eczema in children during the first year of life.
This study included 1330 mother-child pairs who attended the Kuopio Birth Cohort (KuBiCo) study and had dietary information during the last trimester and information on children's health in the first year of life. AHEI-P and DII indicate a healthy diet and dietary inflammation potential during pregnancy. The AHEI-P and DII were compared with reported wheezing and doctor-diagnosed atopic eczema in children during the first year of life.
Neither AHEI-P nor DII is associated with wheezing or atopic eczema in children when analyzed by continuous variables and by tertiles. The odds ratio (95% CI) for AHEI-P and wheezing was 0.99 (0.98-1.01), for AHEI-P and atopic eczema1.01 (0.99-1.02), for DII and wheezing 1.02 (0.95-1.09), and for DII and atopic eczema 0.97 (0.91-1.04).
In this cohort study, AHEI-P and DII during pregnancy were not associated with wheezing or atopic eczema in the offspring during the first year of life.
最近有几项研究调查了孕妇在怀孕期间的饮食与儿童喘息或哮喘之间的关系。然而,怀孕期间特定的饮食模式是否能保护儿童免受喘息或特应性疾病的影响仍不清楚。本研究调查了妊娠替代健康饮食指数(AHEI-P)、饮食炎症指数(DII)与儿童生命第一年喘息和特应性湿疹风险之间的关系。
这项研究包括 1330 对母婴对,他们参加了库奥皮奥出生队列(KuBiCo)研究,并在妊娠最后三个月有饮食信息,以及儿童生命第一年的健康信息。AHEI-P 和 DII 表明孕妇的饮食健康和饮食炎症潜力。将 AHEI-P 和 DII 与儿童生命第一年报告的喘息和医生诊断的特应性湿疹进行比较。
无论是 AHEI-P 还是 DII,在连续变量和三分位组分析中,与儿童喘息或特应性湿疹均无相关性。AHEI-P 和喘息的比值比(95%CI)为 0.99(0.98-1.01),AHEI-P 和特应性湿疹为 1.01(0.99-1.02),DII 和喘息为 1.02(0.95-1.09),DII 和特应性湿疹为 0.97(0.91-1.04)。
在这项队列研究中,孕妇在怀孕期间的 AHEI-P 和 DII 与儿童生命第一年的喘息或特应性湿疹无关。