Department of Urology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Department of Radiology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Ann Surg Oncol. 2024 Jun;31(6):3880-3886. doi: 10.1245/s10434-024-15106-1. Epub 2024 Mar 8.
We aimed to evaluate the risk factors for the conversion from laparoscopic partial nephrectomy (LPN) to open surgery to achieve partial nephrectomy (PN).
Data from patients who underwent LPN between June 2020 and September 2023 were analyzed retrospectively. Patients in whom the PN procedure could be completed laparoscopically were recorded as the 'Fully Laparoscopic' (FL) group (n = 97), and those converted to open surgery from laparoscopy were recorded as the 'Conversion to Open' (CTO) group (n = 10). The demographic and pathologic variables were compared between groups. Regression analyses were used to define predictor factors, and receiver operating characteristic analysis was used to define the cut-off value of the surgical bleeding volume.
Conversion to open surgery was found in 10/107 patients (9.3%). There was no statistical difference between groups in demographic and pathologic variables. Intraoperative blood loss volume, upper pole localized tumor, and posterior localized tumor were found to be statistically higher in the CTO group (p = 0.001, p = 0.001, and p = 0.043, respectively). Furthermore, these factors were only found to be statistically significant predictors of conversion to open surgery in both univariate and multivariate regression analyses. 235 cc was found to be the cut-off value of intraoperative blood loss volume for predicting conversion to open surgery (p = 0.001).
Using these predictive factors in clinical practice, treatment planning will lead to the possibility of starting the treatment directly with open surgery instead of minimally invasive options, and it may also provide a chance of being prepared for the possibility of conversion to open surgery peroperatively.
我们旨在评估腹腔镜部分肾切除术(LPN)转为开放手术以实现部分肾切除术(PN)的风险因素。
回顾性分析 2020 年 6 月至 2023 年 9 月期间接受 LPN 的患者数据。能够通过腹腔镜完成 PN 手术的患者记录为“完全腹腔镜”(FL)组(n=97),而从腹腔镜转为开放手术的患者记录为“转为开放”(CTO)组(n=10)。比较两组的人口统计学和病理变量。使用回归分析定义预测因素,使用受试者工作特征分析定义手术出血量的截断值。
在 107 例患者中发现 10 例(9.3%)转为开放手术。两组在人口统计学和病理变量方面无统计学差异。术中出血量、上极局限性肿瘤和后极局限性肿瘤在 CTO 组中明显更高(p=0.001、p=0.001 和 p=0.043)。此外,这些因素在单因素和多因素回归分析中仅被发现是转为开放手术的统计学显著预测因素。术中出血量 235cc 被发现是预测转为开放手术的截断值(p=0.001)。
在临床实践中使用这些预测因素,治疗计划将有可能直接采用开放手术而不是微创选择,并且还可能为术中转为开放手术做好准备。