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一项针对青少年的基于学校的皮肤癌预防干预措施的整群随机试验方案。

Protocol for a cluster-randomized trial of a school-based skin cancer preventive intervention for adolescents.

作者信息

Wu Yelena P, Stump Tammy K, Hay Jennifer L, Buller David B, Jensen Jakob D, Grossman Douglas, Shen Jincheng, Haaland Benjamin A, Jones Jacey, Tercyak Kenneth P

机构信息

Department of Dermatology, University of Utah, 30 N. Mario Capecchi Dr., Salt Lake City, UT 84112, USA; Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112, USA.

Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

出版信息

Contemp Clin Trials. 2024 May;140:107494. doi: 10.1016/j.cct.2024.107494. Epub 2024 Mar 6.

Abstract

BACKGROUND

Adolescents infrequently use sun protection and engage in intentional tanning more frequently compared to other age groups, leading to increased ultraviolet radiation (UVR) exposure that heightens skin cancer risk across the lifespan. High schools are therefore an ideal setting for offering skin cancer preventive interventions. Yet, there are limited UVR protection interventions for high school students, especially those that are personalized, tested using randomized designs, and include long-term outcome assessment to determine the durability of intervention effects.

METHOD

The Sun-safe Habits Intervention and Education (SHINE) cluster-randomized trial will test a novel, personalized intervention that targets high school adolescents' sun protection and tanning behaviors, and tracks their outcomes for up to one year following intervention. Enrolled high schools will be randomized to receive either the personalized SHINE intervention, which includes facial UVR photographs and sun protection action planning, or standard education using publicly available materials. Students in both conditions will receive information about skin cancer, sun protection, and skin self-examination. Outcome variables will include students' sun protection and tanning behaviors and sunburn occurrence. Potential moderators (e.g., race/ethnicity) and mediators (e.g., self-efficacy) will also be assessed and tested.

CONCLUSIONS

This trial examines the efficacy of a personalized intervention targeting sun protection and tanning of high school students. The project will lead to new scientific understanding of the theoretical mechanisms underlying outcomes and moderators of the intervention effects, which will inform future intervention tailoring to meet the needs of vulnerable subgroups.

摘要

背景

与其他年龄组相比,青少年很少使用防晒措施,且更频繁地进行刻意晒黑,这导致紫外线辐射(UVR)暴露增加,从而在整个生命周期内增加了皮肤癌风险。因此,高中是开展皮肤癌预防干预的理想场所。然而,针对高中生的紫外线防护干预措施有限,尤其是那些个性化的、采用随机设计进行测试并包括长期结果评估以确定干预效果持久性的措施。

方法

“阳光安全习惯干预与教育”(SHINE)整群随机试验将测试一种新颖的个性化干预措施,该措施针对高中青少年的防晒和晒黑行为,并在干预后长达一年的时间内跟踪其结果。入选的高中将被随机分配接受个性化的SHINE干预,其中包括面部紫外线照片和防晒行动计划,或使用公开可用材料进行标准教育。两种情况下的学生都将获得有关皮肤癌、防晒和皮肤自我检查的信息。结果变量将包括学生的防晒和晒黑行为以及晒伤发生率。还将评估和测试潜在的调节因素(例如种族/族裔)和中介因素(例如自我效能感)。

结论

本试验检验了针对高中生防晒和晒黑的个性化干预措施的效果。该项目将使人们对干预效果的结果和调节因素背后的理论机制有新的科学认识,这将为未来的干预措施量身定制提供参考,以满足弱势群体的需求。

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A four-group experiment to improve Western high school students' sun protection behaviors.
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