Department of Human Nutrition, College of Health Science, Qatar University, Doha P.O. Box 2713, Qatar.
Nutrients. 2024 Feb 20;16(5):579. doi: 10.3390/nu16050579.
Breast cancer (BC) is the most predominant malignancy in Arab women in the Middle East, and yearly increases in occurrence by 37.5 and mortality rates by 15.2 for every 100,000 in 2019. This review explores the gap in research investigating the role of dietary patterns and BC in Middle Eastern countries. Furthermore, we analyze the evidence connecting these patterns to BC prevalence in the region, discussing implications for public health and preventive strategies. PubMed, ProQuest, and Cochrane databases were searched up to November 2023. Articles published in English from 2000 to 2023 were identified. Our search included dietary patterns (DP), their association with BC and specific to Middle Eastern Regions. The majority of existing research is concentrated in Iran, with limited illustration from Saudi Arabia, Turkey, and Jordan, and a notable absence of studies from other Middle Eastern countries. We found that dietary intervention is closely related to the occurrence, development, and prognosis of BC. Most DPs such as the Dietary Approaches to Stop Hypertension, Mediterranean, Plant-based and Paleolithic diets are identified to decrease the probability of BC by being rich sources of fiber, healthy fats, and vitamins and minerals. However, there are few DPs that increase the risk of BC, because of the existence of foods such as unhealthy fats, low fiber, sugars, and fried foods in those patterns which contribute to increasing the risk factors associated with BC. This review highlights the intricate connection between DPs and the risk of BC in the Middle East, revealing potential protective effects and heightened risks linked to specific dietary elements.
在中东,乳腺癌(BC)是阿拉伯女性中最常见的恶性肿瘤,2019 年,每 10 万人中乳腺癌发病率每年增加 37.5%,死亡率增加 15.2%。本综述探讨了在中东国家研究饮食模式与乳腺癌之间关系的研究差距。此外,我们分析了将这些模式与该地区乳腺癌患病率联系起来的证据,讨论了对公共卫生和预防策略的影响。检索了 PubMed、ProQuest 和 Cochrane 数据库,截至 2023 年 11 月。确定了 2000 年至 2023 年以英语发表的文章。我们的搜索包括饮食模式(DP)及其与 BC 的关系,以及特定于中东地区的关系。现有的大多数研究都集中在伊朗,沙特阿拉伯、土耳其和约旦的研究较少,其他中东国家的研究也很少。我们发现,饮食干预与 BC 的发生、发展和预后密切相关。大多数 DP,如饮食方法阻止高血压、地中海、植物性和原始饮食,被认为是通过富含纤维、健康脂肪、维生素和矿物质来降低患乳腺癌的概率。然而,也有一些 DP 会增加患乳腺癌的风险,因为这些模式中存在不健康脂肪、低纤维、糖和油炸食品等食物,这会增加与乳腺癌相关的风险因素。本综述强调了 DP 与中东地区 BC 风险之间的复杂联系,揭示了特定饮食因素与保护作用和风险增加之间的潜在联系。