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美国医疗监测项目中已确诊感染艾滋病毒的成年人的自评健康状况与艾滋病毒相关结果

Self-rated health and HIV outcomes among adults with diagnosed HIV - Medical Monitoring Project, United States.

作者信息

Cholli Preetam A, Buchacz Kate M, Harris Norma S, Crim Stacy M, Yuan Xin, Tie Yunfeng, Koenig Linda J, Beer Linda

机构信息

Division of HIV Prevention, Centers for Disease Control and Prevention.

Epidemic Intelligence Service, Centers for Disease Control and Prevention.

出版信息

AIDS. 2024 Jul 1;38(8):1237-1247. doi: 10.1097/QAD.0000000000003890. Epub 2024 Mar 19.

Abstract

OBJECTIVES

To evaluate associations between self-rated health (SRH) and care outcomes among United States adults with diagnosed HIV infection.

DESIGN

We analyzed interview and medical record data collected during June 2020-May 2021 from the Medical Monitoring Project, a complex, nationally representative sample of 3692 people with HIV (PWH). Respondents reported SRH on a 5-point Likert type scale (poor to excellent), which we dichotomized into "good or better" and "poor or fair". We computed weighted percentages with 95% confidence intervals (CIs) and age-adjusted prevalence ratios (aPRs) to investigate associations between SRH and HIV outcomes and demographic, psychosocial, and behavioral characteristics.

RESULTS

Nationally, 72% of PWH reported "good or better" SRH. PWH with the following characteristics had a lower prevalence of "good or better" SRH, compared with those without: any missed HIV care appointment in the last 12 months (aPR 0.86, 95% CI: 0.81-0.91), symptoms of moderate or severe depression (aPR 0.51, 95% CI: 0.43-0.59) and anxiety (aPR 0.60, 95% CI: 0.54-0.68), unstable housing or homelessness (aPR 0.77, 95% CI: 0.71-0.82), and hunger or food insecurity (aPR 0.74, 95% CI: 0.69-0.80), as well as having a mean CD4 count <200 cells/mm 3 vs. CD4 + >500 cells/mm 3 (aPR 0.70, 95% CI: 0.57-0.86).

CONCLUSIONS

Though SRH is a holistic measure reflective of HIV outcomes, integrated approaches addressing needs beyond physical health are necessary to improve SRH among PWH in the United States. Modifiable factors like mental health, unstable housing or homelessness, and food insecurity warrant further study as potential high-yield targets for clinical and policy interventions to improve SRH among PWH.

摘要

目的

评估美国已确诊感染艾滋病毒的成年人的自评健康状况(SRH)与护理结果之间的关联。

设计

我们分析了2020年6月至2021年5月期间从医疗监测项目收集的访谈和病历数据,该项目是一个复杂的、具有全国代表性的3692名艾滋病毒感染者(PWH)样本。受访者用5分李克特量表(从差到优)报告自评健康状况,我们将其分为“良好或更好”和“差或一般”。我们计算了加权百分比及95%置信区间(CIs)和年龄调整患病率比(aPRs),以研究自评健康状况与艾滋病毒结果以及人口统计学、心理社会和行为特征之间的关联。

结果

在全国范围内,72%的艾滋病毒感染者报告自评健康状况为“良好或更好”。与没有以下特征的艾滋病毒感染者相比,有以下特征的感染者“良好或更好”自评健康状况的患病率较低:在过去12个月内有任何错过的艾滋病毒护理预约(aPR 0.86,95% CI:0.81 - 0.91)、中度或重度抑郁症状(aPR 0.51,95% CI:0.43 - 0.59)和焦虑症状(aPR 0.60,95% CI:0.54 - 0.68)、住房不稳定或无家可归(aPR 0.77,95% CI:0.71 - 0.82)、饥饿或粮食不安全(aPR 0.74,95% CI:0.69 - 0.80),以及平均CD4细胞计数<200个/mm³ 与CD4⁺>500个/mm³ 相比(aPR 0.70,95% CI:0.57 - 0.86)。

结论

尽管自评健康状况是反映艾滋病毒结果的一项综合指标,但在美国,需要采取综合方法来满足身体健康以外的需求,以改善艾滋病毒感染者的自评健康状况。心理健康、住房不稳定或无家可归以及粮食不安全等可改变因素作为改善艾滋病毒感染者自评健康状况的临床和政策干预潜在高收益目标,值得进一步研究。

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