Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
Department of Clinical Sciences, Psychiatry, Lund University, Lund, Sweden; Office of Psychiatry and Habilitation, Region Skåne, Lund, Sweden.
J Affect Disord. 2024 Jun 15;355:317-324. doi: 10.1016/j.jad.2024.03.118. Epub 2024 Mar 27.
The literature on the relationship between anxiety and suicidal behaviors is limited and findings are mixed. This study sought to determine whether physicians noted anxiety symptoms and suicidality in their patients in the weeks and months before suicide.
Data were derived from a nationwide medical record review of confirmed suicides in Sweden in 2015. Individuals with at least one documented physician consultation in any health care setting during 12 months before suicide (N = 956) were included. Clinical characteristics were compared between decedents with and without a notation of anxiety symptoms. Odds ratios were calculated to estimate associations between anxiety symptoms and suicidality in relation to suicide proximity.
Anxiety symptoms were noted in half of individuals 1 week before suicide. Patients with anxiety were characterized by high rates of depressive symptoms, ongoing substance use issues, sleeping difficulties, and fatigue. After adjustment for mood disorders, the odds of having a notation of elevated suicide risk 1 week before death were doubled in persons with anxiety symptoms. Associations were similar across time periods (12 months - 1 week). Two-thirds had been prescribed antidepressants at time of death.
Data were based on physicians' notations which likely resulted in underreporting of anxiety depending on medical specialty. Records were not available for all decedents.
Anxiety symptoms were common in the final week before suicide and were accompanied by increases in documented elevated suicide risk. Our findings can inform psychiatrists, non-psychiatric specialists, and GPs who meet and assess persons with anxiety symptoms.
关于焦虑与自杀行为之间关系的文献有限,研究结果也存在差异。本研究旨在确定医生是否在自杀前数周和数月记录了患者的焦虑症状和自杀意念。
数据来自 2015 年瑞典全国范围内对确诊自杀病例的医疗记录回顾。研究纳入了在自杀前 12 个月内至少有一次在任何医疗保健场所就诊记录的个体(N=956)。比较了有和无焦虑症状记录的死者之间的临床特征。计算比值比以估计焦虑症状与自杀意念与自杀的接近程度之间的关联。
在自杀前 1 周,有一半的个体出现了焦虑症状。有焦虑症状的患者表现出较高的抑郁症状、持续的物质使用问题、睡眠困难和疲劳发生率。在调整了心境障碍后,有焦虑症状的人在死亡前 1 周有记录的自杀风险升高的可能性增加了一倍。关联在各个时间段(12 个月至 1 周)都相似。三分之二的人在死亡时被开具了抗抑郁药。
数据基于医生的记录,根据医疗专业的不同,可能导致焦虑的报告不足。并非所有死者的记录都可用。
在自杀前的最后一周,焦虑症状很常见,同时伴有记录到的自杀风险升高。我们的发现可以为遇到并评估有焦虑症状的精神科医生、非精神科专家和全科医生提供信息。