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利用临床判断的特征改善急诊科疾病严重程度评估:一项Acutelines研究

Exploiting the Features of Clinical Judgment to Improve Assessment of Disease Severity in the Emergency Department: An Acutelines Study.

作者信息

Visser Martje, Rossi Daniel, Bouma Hjalmar R, Ter Maaten Jan C

机构信息

Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.

Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.

出版信息

J Clin Med. 2024 Feb 27;13(5):1359. doi: 10.3390/jcm13051359.

Abstract

BACKGROUND

Clinical judgment, also known as gestalt or gut feeling, can predict deterioration and can be easily and rapidly obtained. To date, it is unknown what clinical judgement precisely entails. The aim of this study was to elucidate which features define the clinical impression of health care professionals in the ED.

METHOD

A nominal group technique (NGT) was used to develop a consensus-based instrument to measure the clinical impression score (CIS, scale 1-10) and to identify features associated with either a more severe or less severe estimated disease severity. This single-center observational cohort study included 517 medical patients visiting the ED. The instrument was prospectively validated.. The predictive value of each feature for the clinical impression was assessed using multivariate linear regression analyses to adjust for potential confounders and validated in the infection group.

RESULTS

The CIS at the ED was associated with ICU admission (OR 1.67 [1.37-2.03], < 0.001), in-hospital mortality (OR 2.25 [1.33-3.81], < 0.001), and 28-day mortality (OR 1.33 [1.07-1.65], <0.001). Dry mucous membranes, eye glance, red flags during physical examination, results of arterial blood gas analysis, heart and respiratory rate, oxygen modality, triage urgency, and increased age were associated with a higher estimated disease severity (CIS). On the other hand, behavior of family, self-estimation of the patient, systolic blood pressure, and Glascow Coma Scale were associated with a lower estimated disease severity (CIS).

CONCLUSION

We identified several features that were associated with the clinical impression of health care professionals in the ED. Translating the subjective features and objective measurements into quantifiable parameters may aid the development of a novel triage tool to identify patients at risk of deterioration in the ED.

摘要

背景

临床判断,也被称为整体感知或直觉,能够预测病情恶化,且能轻松快速地得出。迄今为止,尚不清楚临床判断具体包含哪些内容。本研究的目的是阐明哪些特征决定了急诊科医护人员的临床印象。

方法

采用名义群体技术(NGT)开发一种基于共识的工具,以测量临床印象评分(CIS,范围为1 - 10),并识别与估计疾病严重程度较高或较低相关的特征。这项单中心观察性队列研究纳入了517名到急诊科就诊的内科患者。该工具进行了前瞻性验证。使用多元线性回归分析评估每个特征对临床印象的预测价值,以调整潜在混杂因素,并在感染组中进行验证。

结果

急诊科的CIS与入住重症监护病房(OR 1.67 [1.37 - 2.03],P < 0.001)、院内死亡率(OR 2.25 [1.33 - 3.81],P < 0.001)和28天死亡率(OR 1.33 [1.07 - 1.65],P < 0.001)相关。口腔黏膜干燥、眼神、体格检查中的警示信号、动脉血气分析结果、心率和呼吸频率、吸氧方式、分诊紧迫性以及年龄增加与较高的估计疾病严重程度(CIS)相关。另一方面,家属行为、患者自我评估、收缩压和格拉斯哥昏迷量表与较低的估计疾病严重程度(CIS)相关。

结论

我们识别出了一些与急诊科医护人员临床印象相关的特征。将主观特征和客观测量转化为可量化参数可能有助于开发一种新型分诊工具,以识别急诊科中病情恶化风险的患者。

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