无细胞再生牙髓治疗的进展与展望
Progress and perspectives on cell-free regenerative endodontic therapy.
作者信息
Zhou Jian, Su Yingying, Wang Song-Ling
机构信息
Beijing Laboratory of Oral Health, Capital Medical University, Beijing 100069, China.
Dept. of VIP Dental Service, Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China.
出版信息
Hua Xi Kou Qiang Yi Xue Za Zhi. 2022 Jan 25;40(1):1-6. doi: 10.7518/hxkq.2022.01.001.
Although teeth with pulpitis/apical periodontitis are saved after successful endodontic therapy, they are devitalized and susceptible to reinfections and fractures. The development of biology-based approaches for dental pulp regeneration or repair is possible today because of recent advances in tissue engineering and biomaterials. Cell-free regenerative endodontic therapy offers a promising strategy for the treatment of necrotic immature permanent teeth in children and adolescents. However, studies are underway to determine whether this procedure can be applied to mature teeth.
尽管牙髓炎/根尖周炎患牙在成功的根管治疗后得以保留，但它们已失去活力，易再次感染和发生折断。由于组织工程学和生物材料方面的最新进展，如今基于生物学的牙髓再生或修复方法的开发成为可能。无细胞再生性根管治疗为治疗儿童和青少年坏死的未成熟恒牙提供了一种有前景的策略。然而，目前正在进行研究以确定该方法是否可应用于成熟恒牙。
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