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绿茶在眼部疾病中的潜在治疗作用,一篇综述。

Potential therapeutic effects of green tea () in eye diseases, a review.

作者信息

Boroughani Mohadese, Tahmasbi Zahra, Heidari Mohamad Mahdi, Johari Mohammadkarim, Hashempur Mohammad Hashem, Heydari Mojtaba

机构信息

Student research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.

Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Heliyon. 2024 Mar 27;10(7):e28829. doi: 10.1016/j.heliyon.2024.e28829. eCollection 2024 Apr 15.

Abstract

This review aims to evaluate the therapeutic potential of green tea (GT), scientifically named , in treating eye diseases. We provide an overview of the ingredients and traditional use of , followed by a detailed discussion of its therapeutic uses in various eye diseases, including ocular surface diseases (allergic diseases, dry eye, pterygium, and infections), cataract, glaucoma, uveitis, retinal diseases, and optic nerve diseases. The pharmacologic activities related to ocular diseases, such as anti-vascular endothelial growth factor, aldose reductase inhibitor activity, anti-bacterial, anti-inflammatory, and antioxidant effects are also explored in this review. The dose and route of administration of GT in various studies are discussed. Safety issues related to the use of GT, such as the side effects associated with high doses and long-term use, are also addressed. The review highlights the potential of GT as a natural therapeutic agent for a variety of ocular diseases. Its various pharmacologic activities make it a promising treatment option. However, more well-designed studies are needed to determine the optimal dose and route of administration and to assess its long-term safety and efficacy. Overall, GT appears to be a promising adjunct therapy for various ocular diseases.

摘要

本综述旨在评估科学名称为绿茶(GT)在治疗眼部疾病方面的治疗潜力。我们概述了绿茶的成分和传统用途,随后详细讨论了其在各种眼部疾病中的治疗用途,包括眼表疾病(过敏性疾病、干眼症、翼状胬肉和感染)、白内障、青光眼、葡萄膜炎、视网膜疾病和视神经疾病。本综述还探讨了与眼部疾病相关的药理活性,如抗血管内皮生长因子、醛糖还原酶抑制活性、抗菌、抗炎和抗氧化作用。讨论了不同研究中绿茶的剂量和给药途径。还阐述了与使用绿茶相关的安全问题,如高剂量和长期使用相关的副作用。该综述强调了绿茶作为多种眼部疾病天然治疗剂的潜力。其多种药理活性使其成为一个有前景的治疗选择。然而,需要更多设计良好的研究来确定最佳剂量和给药途径,并评估其长期安全性和疗效。总体而言,绿茶似乎是各种眼部疾病有前景的辅助治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c740/11004586/798cca22e913/gr1.jpg

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