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针刺治疗勃起功能障碍:一项随机对照试验。

Acupuncture for erectile dysfunction: a randomized controlled trial.

机构信息

College of Acupuncture-Moxibustion and Tuina, Chengdu University of TCM, Chengdu 610075, Sichuan Province, China.

College of Acupuncture-Moxibustion and Tuina, Guizhou University of TCM, Guiyang 550025.

出版信息

Zhongguo Zhen Jiu. 2024 Apr 12;44(4):418-422. doi: 10.13703/j.0255-2930.20231005-0001.

Abstract

OBJECTIVES

To observe the clinical efficacy of acupuncture in treating erectile dysfunction (ED).

METHODS

A total of 64 ED patients were randomly divided into an acupuncture group (32 cases, 2 case dropped out) and a western medication group (32 cases, 2 cases dropped out). In the acupuncture group, acupuncture treatment was applied at Baihui (GV 20), Qihai (CV 6), Guanyuan (CV 4), Zhongji (CV 3), Dahe (KI 12), Qugu (CV 2), Zusanli (ST 36), and etc., two groups of acupoints were used alternately, 30 min each time, once every other day. In the western medication group, 50 mg of sildenafil tablet was took orally 1 h before sexual activity. Both groups were treated for 30 d. The international index of erectile function citrate (IIEF-5) score, self rating anxiety scale (SAS) score, self rating depression scale (SDS) score, TCM syndrome score were observed before and after treatment, and in follow-up of 2 weeks after treatment completion, the serum testosterone (T) level was detected before and after treatment, and the clinical efficacy was evaluated in the two groups.

RESULTS

After treatment and in follow-up, the IIEF-5 scores were increased compared with those before treatment in the two groups (0.01). In follow-up, the IIEF-5 score in the acupuncture group was ascended compared with that in the western medication group (0.05). Except for the SDS and TCM syndrome scores in the western medication group of follow-up, the SAS scores, SDS scores, and the TCM syndrome scores were decreased after treatment and in follow-up compared with those before treatment in the two groups (<0.01, <0.05); in the acupuncture group, the SAS scores, SDS scores and the TCM syndrome scores after treatment and in follow-up were lower than those in the western medication group (<0.01). After treatment, the serum T levels were increased compared with those before treatment in the two groups (<0.01). The total effective rate of the acupuncture group was 83.3% (25/30), and it was 86.7% (26/30) in the western medication group, there was no significant difference in total effective rate between the two groups (>0.05).

CONCLUSIONS

Acupuncture can effectively improve erectile function, anxiety and depression state, and TCM syndrome in ED patients, and has a advantage of posterior effect compared with western medication treatment.

摘要

目的

观察针刺治疗勃起功能障碍(ED)的临床疗效。

方法

将 64 例 ED 患者随机分为针刺组(32 例,2 例脱落)和西药组(32 例,2 例脱落)。针刺组针刺百会(GV20)、气海(CV6)、关元(CV4)、中极(CV3)、大河(KI12)、曲骨(CV2)、足三里(ST36)等,两组穴位交替使用,每次 30min,隔日一次。西药组在性活动前 1h 口服 50mg 西地那非片。两组均治疗 30d。观察两组治疗前后国际勃起功能指数问卷-5(IIEF-5)评分、焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分、中医证候评分,治疗后 2 周随访时检测两组患者血清睾酮(T)水平,评价两组临床疗效。

结果

两组治疗后及随访时 IIEF-5 评分均较治疗前升高(P<0.01),针刺组随访时 IIEF-5 评分高于西药组(P<0.05)。除西药组随访时 SDS 评分、中医证候评分外,两组治疗后及随访时 SAS 评分、SDS 评分、中医证候评分均较治疗前降低(P<0.01,P<0.05);针刺组治疗后及随访时 SAS 评分、SDS 评分、中医证候评分均低于西药组(P<0.01)。两组治疗后血清 T 水平均较治疗前升高(P<0.01)。针刺组总有效率为 83.3%(25/30),西药组为 86.7%(26/30),两组总有效率比较差异无统计学意义(P>0.05)。

结论

针刺治疗能有效改善 ED 患者的勃起功能、焦虑抑郁状态及中医证候,且在改善后效应方面优于西药治疗。

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