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微创与开放技术治疗胸腰椎和腰椎脊柱结核的疗效:一项前瞻性对比研究

Outcomes of Dorsolumbar and Lumbar Spinal Tuberculosis Treated by Minimally Invasive and Open Techniques: A Prospective Comparative Study.

作者信息

Ifthekar Syed, Ahuja Kaustubh, Mittal Samarth, Yadav Gagandeep, Chaturvedi Jiitender, Sarkar Bhaskar, Kandwal Pankaj

机构信息

Department of Orthopaedics, All India Institute of Medical Sciences, Rishikesh, Uttarakhand India.

Department of Orthopaedics, All India Institute of Medical Sciences, Bibinagar, Hyderabad, India.

出版信息

Indian J Orthop. 2024 Mar 20;58(5):558-566. doi: 10.1007/s43465-024-01123-5. eCollection 2024 May.

Abstract

PURPOSE OF STUDY

To compare the outcomes of minimally invasive and open techniques in the surgical management of dorsolumbar and lumbar spinal tuberculosis (STB).

METHODS

Skeletally mature patients with active STB involving thoracolumbar and lumbar region confirmed by radiology (X-ray, MRI) and histopathological examination were included. Healed and mechanically stable STB, patients having severe hepatic and renal impairment, coexisting spinal conditions such as ankylosing spondylitis and rheumatoid arthritis, and patients unwilling to participate were excluded from the study. The patients were divided in to two groups, group A consisted of patients treated by MIS techniques and group B consisted of patients treated by open techniques. All the patients had a minimum follow-up of 24 months.

RESULTS

A total of 42 patients were included in the study. MIS techniques were used in 18 patients and open techniques were used in 24 patients. On comparison between the two groups, blood loss (234 ml vs 742 ml), and immediate post-operative VAS score (5.26 vs 7.08) were significantly better in group A, whereas kyphotic correction (16° vs 33.25°) was significantly better in group B. Rest of the parameters such as duration of surgery, VAS score, ODI score and number of instrumented levels did not show significant difference between the two groups.

CONCLUSION

MIS stabilization when compared to open techniques is associated with significant improvement in immediate post-operative VAS scores. The MIS approaches at 2-year follow-up have functional results similar to open techniques. MIS is inferior to open techniques in kyphosis correction and may be associated with complications.

摘要

研究目的

比较微创技术与开放技术在胸腰段和腰椎脊柱结核(STB)手术治疗中的效果。

方法

纳入经放射学检查(X线、MRI)及组织病理学检查确诊的胸腰段和腰椎活动性STB的骨骼成熟患者。已愈合且力学稳定的STB患者、严重肝肾功能损害患者、并存脊柱疾病如强直性脊柱炎和类风湿关节炎患者以及不愿参与者被排除在研究之外。患者分为两组,A组由采用微创技术治疗的患者组成,B组由采用开放技术治疗的患者组成。所有患者均至少随访24个月。

结果

本研究共纳入42例患者。18例患者采用微创技术,24例患者采用开放技术。两组比较,A组的失血量(234 ml对742 ml)和术后即刻视觉模拟评分(VAS)(5.26对7.08)明显更好,而B组的后凸矫正(16°对33.25°)明显更好。手术时间、VAS评分、Oswestry功能障碍指数(ODI)评分及固定节段数等其他参数在两组间无显著差异。

结论

与开放技术相比,微创内固定术可使术后即刻VAS评分显著改善。微创方法在2年随访时的功能结果与开放技术相似。微创技术在矫正后凸方面不如开放技术,且可能伴有并发症。

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