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释放潜力:关于捐赠人乳对婴儿健康结局影响的系统文献综述

Unlocking the Potential: A Systematic Literature Review on the Impact of Donor Human Milk on Infant Health Outcomes.

作者信息

Kashyap Vijiya, Choudhari Sonali G

机构信息

Department of Community Medicine, Jawaharlal Nehru Medical College, School of Epidemiology and Public Health, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2024 Apr 2;16(4):e57440. doi: 10.7759/cureus.57440. eCollection 2024 Apr.

Abstract

Human mother milk is considered the most healthy and best source of nutrition for both premature and full-term infants, as it possesses many health benefits and is associated with its consumption. Some of the mothers are not able to produce an adequate quantity of milk to meet the required needs of the infants, particularly in cases involving premature births or facing challenges in breastfeeding. Especially for the most vulnerable premature infants, donor human milk (DHM) provides a helpful bridge for effective breastfeeding. Even with the advancement in baby formulas, no other dietary source can match the bioactive matrix of benefits found in human breast milk. This literature review discusses the risks associated with prematurity and explores the use of DHM in the care of premature infants. It helps prevent substantial preterm complications, especially necrotizing enterocolitis, bronchopulmonary dysplasia, and late-onset sepsis, which are more commonly seen in infants who are given formulated milk made from cow's milk. It gives insights into the benefits of DHM, such as immunological and nutritional benefits, which is a basic infant's need. When medical distress prevents mothers from producing enough breast milk for their infants, pasteurized human donor breast milk should be made accessible as an alternative feeding option to ensure infants remain healthy and nourished. A systematic literature search was conducted using PubMed and Google Scholar databases and other sources. A total of 104 articles were searched, of which 35 were included after identification, filters were applied, eligibility was checked, and references out of scope were excluded. Human milk banking should be incorporated into programs encouraging breastfeeding, highlighting lactation in mothers and only using DHM when required.

摘要

人乳被认为是早产儿和足月儿最健康、最佳的营养来源,因为它有许多健康益处且与食用人乳相关。一些母亲无法分泌足够量的乳汁来满足婴儿的需求,特别是在早产或母乳喂养面临挑战的情况下。尤其对于最脆弱的早产儿来说,捐赠人乳(DHM)为有效母乳喂养提供了有益的桥梁。即使婴儿配方奶粉有所进步,但没有其他饮食来源能与母乳中发现的有益生物活性基质相匹配。这篇文献综述讨论了与早产相关的风险,并探讨了在早产儿护理中使用捐赠人乳的情况。它有助于预防大量早产并发症,尤其是坏死性小肠结肠炎、支气管肺发育不良和晚发性败血症,这些并发症在食用以牛奶制成的配方奶的婴儿中更为常见。它深入探讨了捐赠人乳的益处,如免疫和营养益处,这是婴儿的基本需求。当医疗困境使母亲无法为婴儿分泌足够的母乳时,应提供巴氏消毒的捐赠人乳作为替代喂养选择,以确保婴儿保持健康和营养充足。使用PubMed和谷歌学术数据库以及其他来源进行了系统的文献检索。共检索到104篇文章,经过识别、应用筛选条件、检查合格性并排除范围外的参考文献后,纳入了35篇。人乳库应纳入鼓励母乳喂养的项目中,强调母亲的泌乳情况,并且仅在必要时使用捐赠人乳。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e5c/11064102/b2385f1985dd/cureus-0016-00000057440-i01.jpg

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