Ebrahim Mohamed A, Zaher Eli A, Patel Parth, Ahmed Marwan K, Ahmed Kanwal
Internal Medicine, Ascension Saint Joseph - Chicago, Chicago, USA.
Cureus. 2024 Apr 13;16(4):e58187. doi: 10.7759/cureus.58187. eCollection 2024 Apr.
This case report presents a unique instance of ascites in acute alcoholic hepatitis (AH) occurring in a non-cirrhotic patient. Comprehensive diagnostic evaluation excluded alternative etiologies, pinpointing sinusoidal non-cirrhotic portal hypertension. Present therapeutic modalities for AH, including steroids and pentoxifylline, offer limited efficacy, necessitating ongoing investigation. Liver transplantation may be contemplated in refractory cases. This case underscores the intricate nature of AH presentations and the challenges in their management, emphasizing the imperative need for continued research to delineate optimal therapeutic strategies. Early intervention remains pivotal in addressing AH complications, underscoring the need for heightened clinical vigilance and proactive treatment approaches in such cases.
本病例报告展示了一名非肝硬化患者急性酒精性肝炎(AH)出现腹水的独特病例。全面的诊断评估排除了其他病因,确定为窦性非肝硬化门静脉高压症。目前针对AH的治疗方法,包括使用类固醇和己酮可可碱,疗效有限,仍需持续研究。难治性病例可能需要考虑肝移植。该病例凸显了AH临床表现的复杂性及其管理中的挑战,强调了继续开展研究以确定最佳治疗策略的迫切需求。早期干预对于应对AH并发症仍然至关重要,突出了在此类病例中提高临床警惕性和采取积极治疗方法的必要性。