Partovi Omeed, Rayes Ramsey, Bureau Britta L, Strohbeen Stephanie, Asmi Nisar
Department of Internal Medicine, Medical College of Wisconsin, Milwaukee, USA.
Department of Neurology, Medical College of Wisconsin, Milwaukee, USA.
Cureus. 2024 Apr 28;16(4):e59214. doi: 10.7759/cureus.59214. eCollection 2024 Apr.
A 38-year-old nulliparous woman with severe obesity (BMI 66) and hypertension presented with constipation, fatigue, weakness, and poor appetite that had progressively worsened over the prior two to three weeks. Upon admission, the patient was found to have significant hypercalcemia, leukocytosis, and lactic acidosis. Computed tomography (CT) scan of the chest, abdomen, and pelvis revealed an adnexal mass with extensive lesions throughout her pelvis, abdomen, and chest. An ultrasound-guided omental core biopsy was performed, which was confirmatory for metastatic ovarian small cell carcinoma. Given her poor prognosis and clinical status, chemotherapy was likely to provide minimal benefit and ultimately the patient decided to pursue a comfort-oriented plan of care and passed away on day 9 of admission.
一名38岁未生育的严重肥胖女性(体重指数66),伴有高血压,出现便秘、疲劳、虚弱和食欲不振症状,在过去两到三周内逐渐加重。入院时,发现该患者有显著的高钙血症、白细胞增多和乳酸性酸中毒。胸部、腹部和骨盆的计算机断层扫描(CT)显示附件有肿块,其骨盆、腹部和胸部有广泛病变。进行了超声引导下的网膜核心活检,确诊为转移性卵巢小细胞癌。鉴于其预后不良和临床状况,化疗可能收效甚微,最终患者决定采取以舒适为导向的护理方案,并于入院第9天去世。