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肿瘤放射药物科学的最新进展和即将面临的挑战。

Recent advances and impending challenges for the radiopharmaceutical sciences in oncology.

机构信息

Departments of Radiology and Chemistry, O'Neal Comprehensive Cancer Center, University of Alabama, Birmingham, AL, USA.

Department of Radiology, University of Michigan, Ann Arbor, MI, USA.

出版信息

Lancet Oncol. 2024 Jun;25(6):e236-e249. doi: 10.1016/S1470-2045(24)00030-5.

Abstract

This paper is the first of a Series on theranostics that summarises the current landscape of the radiopharmaceutical sciences as they pertain to oncology. In this Series paper, we describe exciting developments in radiochemistry and the production of radionuclides, the development and translation of theranostics, and the application of artificial intelligence to our field. These developments are catalysing growth in the use of radiopharmaceuticals to the benefit of patients worldwide. We also highlight some of the key issues to be addressed in the coming years to realise the full potential of radiopharmaceuticals to treat cancer.

摘要

这篇论文是关于放射性药物治疗学的一系列论文中的第一篇,总结了当前放射药物科学在肿瘤学中的现状。在本系列论文中,我们描述了放射化学和放射性核素生产方面令人兴奋的发展,治疗学的开发和转化,以及人工智能在我们领域的应用。这些发展正在促进放射性药物的使用,使全世界的患者受益。我们还强调了未来几年需要解决的一些关键问题,以充分发挥放射性药物治疗癌症的潜力。

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