用于检测静脉输注产品中释放的微（纳）塑料的方案。
Protocol for detecting micro(nano)plastics released from intravenous infusion products.
机构信息
School of Environmental Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
School of Environment, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
出版信息
STAR Protoc. 2024 Jun 21;5(2):103104. doi: 10.1016/j.xpro.2024.103104. Epub 2024 Jun 10.
Approaches for detecting micro(nano)plastics (MNPs) released from intravenous infusion products (IVIPs) are vital for evaluating the safety of both IVIPs and their derived MNPs on human health, yet current understanding is limited. Here, we present a protocol for detecting polyvinyl chloride (PVC) MNPs by combining Raman spectroscopy, scanning electron microscopy equipped with energy-dispersive X-ray spectroscopy (SEM-EDS), and pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS). We describe steps for collecting, pretreating, and measuring PVC MNPs released from IVIPs. For complete details on the use and execution of this protocol, please refer to Li et al..
检测静脉输注产品（IVIP）中释放的微（纳）塑料（MNPs）的方法对于评估 IVIP 及其衍生 MNPs 对人类健康的安全性至关重要，但目前的认识有限。在这里，我们结合拉曼光谱、扫描电子显微镜配备能量色散 X 射线光谱（SEM-EDS）和热解气相色谱-质谱联用（Py-GC-MS），提出了一种检测聚氯乙烯（PVC）MNPs 的方案。我们描述了从 IVIP 中收集、预处理和测量 PVC MNPs 的步骤。有关该方案使用和执行的完整详细信息，请参考 Li 等人的研究。
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