富血小板血浆在猫退行性关节疾病治疗中的应用：一项探索性病例系列研究。
The use of platelet rich plasma in the treatment of degenerative joint disease in cats: an exploratory case series.
作者信息
Huntingford Janice, Looney Andrea, Johnson James, Miller Lisa
机构信息
Essex Animal Hospital, Essex, ON, Canada.
Central Hospital for Veterinary Medicine, North Haven, CT, United States.
出版信息
Front Vet Sci. 2024 May 28;11:1394055. doi: 10.3389/fvets.2024.1394055. eCollection 2024.
OBJECTIVE
To evaluate the effectiveness of intra-articular autologous Platelet Rich Plasma (PRP) in managing Degenerative Joint Disease (DJD) in cats.
DESIGN
Prospective pilot clinical trial.
METHODS
Six domestic cats with clinically and radiographically diagnosed DJD received intra-articular injections of autologous PRP. Clinical assessments pre and post intra-articular injections were conducted using the Feline Musculoskeletal Pain Index (FMPI, owner assessed) and Visual Analog Scale (VAS, clinician assessed) at baseline, Day 14, Day 28, and Day 42-45.
RESULTS
Significant improvements were noted in both FMPI and VAS scores at the end of the study period, indicating enhanced joint function and reduced pain.
CONCLUSION AND CLINICAL RELEVANCE
The study suggests the potential of PRP therapy as a safe and effective treatment for feline DJD, warranting further research with larger cohorts and longer follow-up to establish comprehensive treatment guidelines.
目的
评估关节内注射自体富血小板血浆（PRP）治疗猫退行性关节病（DJD）的有效性。
设计
前瞻性试点临床试验。
方法
六只经临床和影像学诊断为DJD的家猫接受关节内自体PRP注射。在基线、第14天、第28天和第42 - 45天，使用猫肌肉骨骼疼痛指数（FMPI，由主人评估）和视觉模拟量表（VAS，由临床医生评估）对关节内注射前后进行临床评估。
结果
在研究期结束时，FMPI和VAS评分均有显著改善，表明关节功能增强且疼痛减轻。
结论及临床意义
该研究表明PRP疗法有可能作为猫DJD的一种安全有效的治疗方法，需要进一步开展更大样本量和更长随访时间的研究以制定全面的治疗指南。
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