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摩洛哥乌季达市儿科人群自我药疗使用抗生素的患病率及影响因素

Prevalence and Determinants of the Use of Antibiotics by Self-Medication in the Pediatric Population in Oujda, Morocco.

作者信息

Elhaddadi Hasnae, Hamami Amal, Sara Anane, Elouali Aziza, Babakhouya Abdeladim, Rkain Maria

机构信息

Department of Pediatrics, Mohammed VI University Hospital, Oujda, MAR.

Faculty of Medicine and Pharmacy, Mohammed 1st University, Oujda, MAR.

出版信息

Cureus. 2024 May 12;16(5):e60126. doi: 10.7759/cureus.60126. eCollection 2024 May.

Abstract

OBJECTIVE

Antibiotic resistance driven by antibiotic self-medication and inappropriate use of antibiotics is a growing global health threat. Our study aimed to describe parents' self-medication practices with antibiotics, determine the factors favoring their use in the pediatric population, and assess parents' knowledge of the role of antibiotics and antimicrobial resistance.

MATERIALS AND METHODS

We conducted a cross-sectional study over two months (September and October 2023). Data collection was performed using a questionnaire-guided interview. We included 460 parents of children consulting or hospitalized in the Pediatric Department of the University Hospital Mohammed VI in Oujda, Morocco.

RESULTS

A total of 62% of parents questioned were mothers. Self-medication with antibiotics was noted in 313 families (68%). Parents used antibiotics mainly to treat cough (43%) and fever (24%). Betalactams were the antibiotic class most used by parents (72%). Information on dosage and methods of antibiotic administration was provided by pharmacy staff but was not respected by most parents (78%). Efficacy of treatment (58%), saving consultation costs and time (47%), and the ease of obtaining treatment without a prescription (42%) were reported in the majority of cases as reasons for using antibiotics by self-medication. In our context, the probability of self-medicating with antibiotics in the pediatric population is increased by female gender (OR=1.04), low level of education (OR=1.02), low socio-economic status (OR=1.09), and buying antibiotics without a prescription (OR=1.22).

CONCLUSION

Although antibiotic self-medication in children is a worldwide phenomenon, influenced by several geographical, cultural, and economic factors, there is an urgent need to promote a global health strategy.

摘要

目的

抗生素自我药疗以及抗生素的不当使用所导致的抗生素耐药性,是日益严重的全球健康威胁。我们的研究旨在描述家长使用抗生素进行自我药疗的行为,确定在儿科人群中促使他们使用抗生素的因素,并评估家长对抗生素作用及抗菌药物耐药性的了解情况。

材料与方法

我们在两个月(2023年9月和10月)内开展了一项横断面研究。数据收集通过问卷引导式访谈进行。我们纳入了摩洛哥乌季达穆罕默德六世大学医院儿科就诊或住院儿童的460名家长。

结果

接受询问的家长中,共有62%为母亲。313个家庭(68%)存在使用抗生素自我药疗的情况。家长使用抗生素主要用于治疗咳嗽(43%)和发烧(24%)。β-内酰胺类是家长最常使用的抗生素类别(72%)。药房工作人员提供了抗生素给药剂量和方法的信息,但大多数家长(78%)并未遵循。在大多数情况下,治疗效果(58%)、节省诊疗费用和时间(47%)以及无需处方即可轻松获得治疗(42%)被报告为自我药疗使用抗生素的原因。在我们的研究背景下,儿科人群中自我药疗使用抗生素的可能性因女性性别(比值比=1.04)、低教育水平(比值比=1.02)、低社会经济地位(比值比=1.09)以及无处方购买抗生素(比值比=1.22)而增加。

结论

尽管儿童抗生素自我药疗是一种全球现象,受到多种地理、文化和经济因素的影响,但迫切需要推行一项全球健康战略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdd7/11165378/3debe66926e2/cureus-0016-00000060126-i01.jpg

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