Suppr超能文献

揭示肠道微生物相互作用的动态:关于饮食影响与胃肠道健康精准营养的综述

Unveiling the dynamics of gut microbial interactions: a review of dietary impact and precision nutrition in gastrointestinal health.

作者信息

Shang Zifang, Pai Liu, Patil Sandip

机构信息

Guangdong Engineering Technological Research Center of Clinical Molecular Diagnosis and Antibody Drugs, Meizhou People's Hospital (Huangtang Hospital), Meizhou Academy of Medical Sciences, Meizhou, China.

Department of Haematology and Oncology, Shenzhen Children's Hospital, Shenzhen, China.

出版信息

Front Nutr. 2024 May 30;11:1395664. doi: 10.3389/fnut.2024.1395664. eCollection 2024.

Abstract

The human microbiome, a dynamic ecosystem within the gastrointestinal tract, plays a pivotal role in shaping overall health. This review delves into six interconnected sections, unraveling the intricate relationship between diet, gut microbiota, and their profound impact on human health. The dance of nutrients in the gut orchestrates a complex symphony, influencing digestive processes and susceptibility to gastrointestinal disorders. Emphasizing the bidirectional communication between the gut and the brain, the Brain-Gut Axis section highlights the crucial role of dietary choices in physical, mental, and emotional well-being. Autoimmune diseases, particularly those manifesting in the gastrointestinal tract, reveal the delicate balance disrupted by gut microbiome imbalances. Strategies for reconciling gut microbes through diets, precision nutrition, and clinical indications showcase promising avenues for managing gastrointestinal distress and revolutionizing healthcare. From the Low-FODMAP diet to neuro-gut interventions, these strategies provide a holistic understanding of the gut's dynamic world. Precision nutrition, as a groundbreaking discipline, holds transformative potential by tailoring dietary recommendations to individual gut microbiota compositions, reshaping the landscape of gastrointestinal health. Recent advancements in clinical indications, including exact probiotics, fecal microbiota transplantation, and neuro-gut interventions, signify a new era where the gut microbiome actively participates in therapeutic strategies. As the microbiome takes center stage in healthcare, a paradigm shift toward personalized and effective treatments for gastrointestinal disorders emerges, reflecting the symbiotic relationship between the human body and its microbial companions.

摘要

人类微生物组是胃肠道内的一个动态生态系统,在塑造整体健康方面发挥着关键作用。本综述深入探讨了六个相互关联的部分,揭示了饮食、肠道微生物群之间的复杂关系,以及它们对人类健康的深远影响。肠道内营养物质的相互作用编排了一曲复杂的交响乐,影响着消化过程以及患胃肠道疾病的易感性。“脑-肠轴”部分强调了肠道与大脑之间的双向沟通,突出了饮食选择在身体、心理和情绪健康中的关键作用。自身免疫性疾病,尤其是那些在胃肠道表现出来的疾病,揭示了肠道微生物组失衡所破坏的微妙平衡。通过饮食、精准营养和临床指征来调节肠道微生物的策略,为管理胃肠道不适和变革医疗保健展示了充满希望的途径。从低发酵碳水化合物饮食到神经-肠道干预措施,这些策略提供了对肠道动态世界的全面理解。精准营养作为一门开创性学科,通过根据个体肠道微生物群组成定制饮食建议,具有变革潜力,重塑了胃肠道健康的格局。临床指征方面的最新进展,包括精确的益生菌、粪便微生物群移植和神经-肠道干预措施,标志着一个新时代的到来,即肠道微生物组积极参与治疗策略。随着微生物组在医疗保健中占据中心地位,出现了一种向个性化和有效治疗胃肠道疾病转变的范式,反映了人体与其微生物伙伴之间的共生关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52ca/11169903/01d1375e785a/fnut-11-1395664-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验