了解内皮细胞在胶质母细胞瘤中的作用：机制与新疗法。
Understanding the Role of Endothelial Cells in Glioblastoma: Mechanisms and Novel Treatments.
机构信息
Department of Neurosurgery, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA.
出版信息
Int J Mol Sci. 2024 Jun 1;25(11):6118. doi: 10.3390/ijms25116118.
Glioblastoma is a highly aggressive neoplasm and the most common primary malignant brain tumor. Endothelial tissue plays a critical role in glioblastoma growth and progression, facilitating angiogenesis, cellular communication, and tumorigenesis. In this review, we present an up-to-date and comprehensive summary of the role of endothelial cells in glioblastomas, along with an overview of recent developments in glioblastoma therapies and tumor endothelial marker identification.
胶质母细胞瘤是一种高度侵袭性的肿瘤，也是最常见的原发性恶性脑肿瘤。内皮组织在胶质母细胞瘤的生长和进展中起着至关重要的作用，促进血管生成、细胞通讯和肿瘤发生。在这篇综述中，我们全面介绍了内皮细胞在胶质母细胞瘤中的作用，并概述了胶质母细胞瘤治疗方法的最新进展和肿瘤内皮标志物的鉴定。
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