Suppr超能文献

慢性肌肉骨骼疼痛患者的门诊跨学科多模式疼痛治疗方案:一项纵向队列研究。

Outpatient interdisciplinary multimodal pain treatment programme for patients with chronic musculoskeletal pain: a longitudinal cohort study.

作者信息

Breugelmans L, Smeets R J E M, Köke A J A, Winkens B, Oosterwijk R F A, Beckers L W M E

机构信息

Department of Rehabilitation Medicine, Care and Public Health Research Institute (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.

CIR Clinics in Revalidatie, Netherlands.

出版信息

Disabil Rehabil. 2025 Mar;47(5):1114-1125. doi: 10.1080/09638288.2024.2364822. Epub 2024 Jun 23.

Abstract

PURPOSE

To describe the outcomes of an interdisciplinary multimodal pain treatment (IMPT) for chronic musculoskeletal pain (CMP) patients up until 12 months post-treatment.

MATERIALS AND METHODS

Data were gathered during routine clinical practice during a 3-year period (2019-2021) at six Dutch rehabilitation centres. Assessments included patient-reported outcome measures for multiple domains including disability, pain and fatigue. Longitudinal data were analysed using repeated-measures models and by quantifying responder rates.

RESULTS

Included were 2309 patients with a mean age of 43.7 (SD 12.9) years, of which 73% female. All outcomes showed significant improvements at each timepoint. At discharge, large effect sizes were found for disability, average and worst pain, fatigue and health-related quality of life. Improvements were largely sustained at 12-months. Relatively large proportions of patients had clinically relevant improvements after treatment (pain-related disability: 60%; average pain: 52%; worst pain: 37.4%; work capacity: 50%; concentration: 50%; fatigue: 46%). Patients who received a treatment extension showed further improvements for all outcome measures, except average pain.

CONCLUSIONS

At group level, all outcomes significantly improved with mainly large effect sizes. The results were mostly sustained. The proportion of patients showing clinically relevant improvements tends to be larger than previously reported for mixed CMP patients.

摘要

目的

描述慢性肌肉骨骼疼痛(CMP)患者接受跨学科多模式疼痛治疗(IMPT)直至治疗后12个月的结果。

材料与方法

在荷兰六个康复中心进行的为期3年(2019 - 2021年)的常规临床实践中收集数据。评估包括患者报告的多个领域的结局指标,包括残疾、疼痛和疲劳。使用重复测量模型并通过量化缓解率对纵向数据进行分析。

结果

纳入2309例患者,平均年龄43.7(标准差12.9)岁,其中73%为女性。所有结局指标在每个时间点均显示出显著改善。出院时,在残疾、平均和最严重疼痛、疲劳以及健康相关生活质量方面发现了较大的效应量。改善情况在12个月时基本得以维持。相当大比例的患者在治疗后有临床相关改善(疼痛相关残疾:60%;平均疼痛:52%;最严重疼痛:37.4%;工作能力:50%;注意力:50%;疲劳:46%)。接受延长治疗的患者在所有结局指标上均有进一步改善,但平均疼痛除外。

结论

在组水平上,所有结局指标均显著改善,主要是较大的效应量。结果大多得以维持。显示出临床相关改善的患者比例往往高于先前报道的混合CMP患者。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验