Department of Public and Ecosystem Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.
Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America.
PLoS One. 2024 Jun 25;19(6):e0303019. doi: 10.1371/journal.pone.0303019. eCollection 2024.
Robust testing capacity was necessary for public health agencies to respond to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the coronavirus disease 19 (COVID-19) pandemic. As the nation faced the need for robust testing capacity, it became necessary to use all possible resources. In many cases, veterinary diagnostic laboratories rose to meet this demand because these facilities routinely perform high throughput diagnostic testing of large animal populations and are typically familiar with pathogens of high pandemic concern. In this study, we evaluated the impact of veterinary diagnostic laboratories in the United States on SARS-CoV-2 testing. Results of surveys, semi-structured interviews, and analysis of publicly available information showed that veterinary diagnostic laboratories had a substantial impact on human health through population-level testing in the COVID-19 response, supporting timely and informed public health interventions. This success was not without significant hurdles, as many participating veterinary diagnostic laboratories experienced restriction in their response due to difficulties obtaining the Clinical Laboratory Improvement Amendments (CLIA) certification required to conduct human diagnostic testing. Our results point out the importance of reducing hurdles before the next major public health emergency to enhance access to testing resources overall and to ultimately improve population health.
在 2019 冠状病毒病(COVID-19)大流行期间,公共卫生机构需要强大的检测能力来应对严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)。随着国家面临建立强大检测能力的需求,有必要利用所有可能的资源。在许多情况下,兽医诊断实验室能够满足这一需求,因为这些设施通常对大型动物群体进行高通量诊断检测,并且通常熟悉高关注大流行的病原体。在这项研究中,我们评估了美国兽医诊断实验室对 SARS-CoV-2 检测的影响。调查结果、半结构化访谈和对公开信息的分析表明,兽医诊断实验室通过在 COVID-19 应对中的人群水平检测对人类健康产生了重大影响,支持了及时和明智的公共卫生干预措施。这一成功并非没有重大障碍,因为许多参与的兽医诊断实验室由于难以获得进行人类诊断检测所需的临床实验室改进修正案(CLIA)认证,其应对措施受到限制。我们的研究结果表明,在下一次重大公共卫生紧急情况之前,减少障碍以提高检测资源的可及性并最终改善人口健康非常重要。