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3D 打印在医疗器械和制药领域的编年史:追溯发展历程和历史里程碑。

3D printing chronicles in medical devices and pharmaceuticals: tracing the evolution and historical milestones.

机构信息

School of Pharmacy, Indrashil University, Kadi, Gujarat, India.

Department of Pharmaceutics, Faculty of Pharmacy, Parul University, Vadodara, Gujarat, India.

出版信息

J Biomater Sci Polym Ed. 2024 Dec;35(17):2723-2766. doi: 10.1080/09205063.2024.2386222. Epub 2024 Aug 5.

Abstract

The objective of this study is to collect the significant advancements of 3D printed medical devices in the biomedical area in recent years. Especially related to a range of diseases and the polymers employed in drug administration. To address the existing limitations and constraints associated with the method used for producing 3D printed medical devices, in order to optimize their suitability for degradation. The compilation and use of research papers, reports, and patents that are relevant to the key keywords are employed to improve comprehension. According to this thorough investigation, it can be inferred that the 3D Printing method, specifically Fuse Deposition Modeling (FDM), is the most suitable and convenient approach for preparing medical devices. This study provides an analysis and summary of the development trend of 3D printed implantable medical devices, focusing on the production process, materials specially the polymers, and typical items associated with 3D printing technology. This study offers a comprehensive examination of nanocarrier research and its corresponding discoveries. The FDM method, which is already facing significant challenges in terms of achieving optimal performance and cost reduction, will experience remarkable advantages from this highly valuable technology. The objective of this analysis is to showcase the efficacy and limitations of 3D-printing applications in medical devices through thorough research, highlighting the significant technological advancements it offers. This article provides a comprehensive overview of the most recent research and discoveries on 3D-printed medical devices, offering significant insights into their study.

摘要

本研究旨在收集近年来 3D 打印医疗设备在生物医学领域的重要进展。特别是与一系列疾病和药物输送中使用的聚合物有关。为了解决与用于生产 3D 打印医疗设备的方法相关的现有局限性和约束,以优化其降解的适用性。使用与关键关键词相关的研究论文、报告和专利进行编译和利用,以提高理解能力。根据这项全面调查,可以推断出 3D 打印方法,特别是熔丝制造(FDM),是制备医疗设备最适合和方便的方法。本研究分析和总结了 3D 打印植入式医疗设备的发展趋势,重点介绍了生产工艺、材料特别是聚合物以及与 3D 打印技术相关的典型项目。本研究全面考察了纳米载体的研究及其相应的发现。FDM 方法在实现最佳性能和降低成本方面已经面临重大挑战,将从这项极具价值的技术中获得显著优势。本分析的目的是通过深入研究展示 3D 打印在医疗器械中的应用的功效和局限性,突出其提供的重大技术进步。本文全面概述了 3D 打印医疗设备的最新研究和发现,为其研究提供了重要的见解。

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