Ran Guangquan, Wang Yan, Liu Shuai, Liu Danping
/ ( 610041) Department of Health Behavior and Social Medicine, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2024 Jul 20;55(4):925-931. doi: 10.12182/20240760601.
To investigate the mediating role of depression in the association between multidimensional social deprivation and frailty among the elderly.
A total of 533 elderly individuals were enrolled from a district in Chengdu using a convenience sampling method. The participants responded to a questionnaire survey. Spearman rank correlation coefficient was employed to assess the correlations among social deprivation, depression, and frailty. MacKinnon's product-of-coefficients method was used to test the significance of the mediating effect of depression between social deprivation and frailty.
Among the participants, the average score for social deprivation among the participants was 48.9±7.1, the depression detection rate was 12.8%, and the frailty incidence rate was 8.4%. Social deprivation was positively correlated with frailty (=0.212, <0.001) and depression (=0.399, <0.001), while depression was positively correlated with frailty (=0.248, <0.001). The results of the mediation analysis showed that depression partially mediated the relationship between social deprivation and frailty (<0.05), accounting for 64.95% of the mediation effect. Specifically, depression partially mediated the relationship between socio-economic status, comprehensive feeling, and frailty (<0.05), accounting for 70.30% and 64.76% of the mediating effect, respectively. Depression fully mediated the relationship between family and social support, political and social participation dimensions, and frailty (<0.05).
Social deprivation can influence frailty in elderly people, with depression partially mediating this association.
探讨抑郁在老年人多维社会剥夺与衰弱之间的关联中所起的中介作用。
采用便利抽样法从成都某区招募了533名老年人。参与者进行了问卷调查。采用Spearman等级相关系数评估社会剥夺、抑郁和衰弱之间的相关性。运用MacKinnon系数乘积法检验抑郁在社会剥夺与衰弱之间中介效应的显著性。
参与者中,社会剥夺平均得分为48.9±7.1,抑郁检出率为12.8%,衰弱发生率为8.4%。社会剥夺与衰弱呈正相关(=0.212,<0.001),与抑郁呈正相关(=0.399,<0.001),而抑郁与衰弱呈正相关(=0.248,<0.001)。中介分析结果显示,抑郁部分中介了社会剥夺与衰弱之间的关系(<0.05),占中介效应的64.95%。具体而言,抑郁部分中介了社会经济地位、综合感受与衰弱之间的关系(<0.05),分别占中介效应的70.30%和64.76%。抑郁完全中介了家庭与社会支持、政治与社会参与维度与衰弱之间的关系(<0.05)。
社会剥夺可影响老年人的衰弱,抑郁部分中介了这种关联。