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Editorial overview: Breaking boundaries: new frontiers in chromatin regulation for cancer therapy.

作者信息

Shilatifard Ali, Lauberth Shannon M

机构信息

Simpson Querrey Institute for Epigenetics and Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

出版信息

Curr Opin Genet Dev. 2024 Oct;88:102255. doi: 10.1016/j.gde.2024.102255. Epub 2024 Sep 3.

Abstract
摘要

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本文引用的文献

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Dysregulation of transcriptional condensates in human disease: mechanisms, biological functions, and open questions.
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Hijacked enhancer-promoter and silencer-promoter loops in cancer.
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Chromatin and aberrant enhancer activity in KMT2A rearranged acute lymphoblastic leukemia.
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Therapeutic targeting of BET bromodomain and other epigenetic acetylrecognition domain-containing factors.
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Cohesin regulation and roles in chromosome structure and function.
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