Alvarez-Jimenez M, Nicholas J, Valentine L, Liu P, Mangelsdorf S, Baker S, Gilbertson T, O'Loughlin G, McEnery C, McGorry P D, Gleeson J F, Cross S P
Orygen Digital, Parkville, Australia.
Melbourne, Centre for Youth Mental Health, The University of Melbourne, Australia.
Acta Psychiatr Scand. 2025 Mar;151(3):317-331. doi: 10.1111/acps.13751. Epub 2024 Sep 11.
Youth mental health (YMH) services have been established internationally to provide timely, age-appropriate, mental health treatment and improve long-term outcomes. However, YMH services face challenges including long waiting times, limited continuity of care, and time-bound support. To bridge this gap, MOST was developed as a scalable, blended, multi-modal digital platform integrating real-time and asynchronous clinician-delivered counselling; interactive psychotherapeutic content; vocational support; peer support, and a youth-focused online community. The implementation of MOST within Australian YMH services has been publicly funded.
The primary aim of this study was to evaluate the real-world engagement, outcomes, and experience of MOST during the first 32 months of implementation.
Young people from participating YMH services were referred into MOST. Engagement metrics were derived from platform usage. Symptom and satisfaction measures were collected at baseline, 6, and 12 (primary endpoint) weeks. Effect sizes were calculated for the primary outcomes of depression and anxiety and secondary outcomes of psychological distress and wellbeing.
Five thousand seven hundred and two young people from 262 clinics signed up and used MOST at least once. Young people had an average of 19 login sessions totalling 129 min over the first 12 weeks of use, with 71.7% using MOST for at least 14 days, 40.1% for 12 weeks, and 18.8% for 24 weeks. There was a statistically significant, moderate improvement in depression and anxiety at 12 weeks as measured by the PHQ4 across all users irrespective of treatment stage (d = 0.41, 95% CI 0.35-0.46). Satisfaction levels were high, with 93% recommending MOST to a friend. One thousand one hundred and eighteen young people provided written feedback, of which 68% was positive and 31% suggested improvement.
MOST is a highly promising blended digital intervention with potential to address the limitations and enhance the impact of YMH services.
国际上已设立青少年心理健康(YMH)服务机构,以提供及时、适龄的心理健康治疗并改善长期治疗效果。然而,青少年心理健康服务面临诸多挑战,包括候诊时间长、护理连续性有限以及有时间限制的支持。为弥合这一差距,MOST作为一个可扩展的、混合的、多模式数字平台而开发,该平台整合了实时和异步的临床医生提供的咨询服务;交互式心理治疗内容;职业支持;同伴支持以及一个以青少年为中心的在线社区。在澳大利亚青少年心理健康服务机构中实施MOST已获得公共资金支持。
本研究的主要目的是评估MOST在实施的前32个月内的实际参与度、治疗效果及体验。
来自参与青少年心理健康服务机构的年轻人被转介至MOST。参与度指标源自平台使用情况。在基线、第6周和第12周(主要终点)收集症状和满意度测量数据。计算抑郁和焦虑主要结局以及心理困扰和幸福感次要结局的效应量。
来自262家诊所的5702名年轻人注册并至少使用过一次MOST。在使用的前12周内,年轻人平均登录19次,总计129分钟,71.7%的人使用MOST至少14天,40.1%的人使用12周,18.8%的人使用24周。无论治疗阶段如何,所有用户在第12周时,通过PHQ4测量的抑郁和焦虑均有统计学上显著的中度改善(d = 0.41,95%CI 0.35 - 0.46)。满意度很高,93%的人会向朋友推荐MOST。1118名年轻人提供了书面反馈,其中68%为积极反馈,31%提出了改进建议。
MOST是一种非常有前景的混合数字干预措施,有潜力解决青少年心理健康服务的局限性并增强其影响力。