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从一杯茶到心血管护理:血管作用机制

From a Cup of Tea to Cardiovascular Care: Vascular Mechanisms of Action.

作者信息

Sagris Marios, Vlachakis Panayotis K, Simantiris Spyridon, Theofilis Panagiotis, Gerogianni Maria, Karakasis Paschalis, Tsioufis Konstantinos, Tousoulis Dimitris

机构信息

Hippokration General Hospital, School of Medicine, National and Kapodistrian University of Athens, 15772 Athens, Greece.

Endocrine Unit, 2nd Propaedeutic Department of Internal Medicine, School of Medicine, Research Institute and Diabetes Center, Attikon University Hospital, National and Kapodistrian University of Athens, 12641 Athens, Greece.

出版信息

Life (Basel). 2024 Sep 15;14(9):1168. doi: 10.3390/life14091168.

Abstract

Tea consumption is increasingly recognized for its potential benefits to cardiovascular health. This study reviews the available research, concentrating on the major components of tea and their mechanisms of action in the cardiovascular system. Tea is abundant in bioactive compounds, such as flavonoids and polysaccharides, which possess significant antioxidant and anti-inflammatory properties. These compounds play a crucial role in mitigating oxidative stress and inflammation, thereby supporting cardiovascular health. They enhance endothelial function, leading to improved vascular relaxation and reduced arterial stiffness, and exhibit antithrombotic effects. Additionally, regular tea consumption is potentially associated with better regulation of blood pressure, improved cholesterol profiles, and effective blood sugar control. It has been suggested that incorporating tea into daily dietary habits could be a practical strategy for cardiovascular disease prevention and management. Despite the promising evidence, more rigorous clinical trials are needed to establish standardized consumption recommendations and fully understand long-term effects. This review offers a more comprehensive analysis of the current evidence based on endothelium function and identifies the gaps that future research should address.

摘要

茶的消费因其对心血管健康的潜在益处而越来越受到认可。本研究回顾了现有研究,重点关注茶的主要成分及其在心血管系统中的作用机制。茶富含生物活性化合物,如黄酮类化合物和多糖,它们具有显著的抗氧化和抗炎特性。这些化合物在减轻氧化应激和炎症方面发挥着关键作用,从而支持心血管健康。它们增强内皮功能,导致血管舒张改善和动脉僵硬度降低,并具有抗血栓作用。此外,经常饮茶可能与更好地调节血压、改善胆固醇水平和有效控制血糖有关。有人提出,将茶纳入日常饮食习惯可能是预防和管理心血管疾病的一种实用策略。尽管有这些有前景的证据,但仍需要更严格的临床试验来制定标准化的消费建议并充分了解长期影响。本综述基于内皮功能对当前证据进行了更全面的分析,并确定了未来研究应解决的差距。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2481/11433009/bdc690358133/life-14-01168-g001.jpg

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