应用二维斑点追踪成像和实时三维超声心动图评估阵发性心房颤动患者导管射频消融术后的心功能恢复情况
Evaluation of Cardiac Function Recovery in Patients with Paroxysmal Atrial Fibrillation after Catheter Radiofrequency Ablation Using Two-Dimensional Speckle Tracking Imaging and Real-Time Three-Dimensional Echocardiography.
作者信息
Han Rui, Mei Ying-Chen, Li Hai-Wei, Li Rong-Juan, He Yi-Hua, Wang Ze-Feng, Wu Yong-Quan
机构信息
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Department of Cardiology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, China.
出版信息
Cardiology. 2025;150(2):166-177. doi: 10.1159/000541247. Epub 2024 Sep 27.
INTRODUCTION
The aim of this study was to evaluate the utility of 2D-STI and real-time three-dimensional echocardiography (RT-3DE) in assessing changes in left atrial (LA) structure and function in patients with paroxysmal atrial fibrillation (PAF) post-radiofrequency catheter ablation (RFCA).
METHODS
A retrospective analysis was conducted on 44 PAF patients who underwent RFCA at BA Hospital from March 2022 to March 2023. An age- and gender-matched control group of 32 healthy individuals was also included. Comprehensive echocardiographic parameters including LA dimensions (LAAPD, LALRD), volumes (LAVmin, LAVmax), ejection fraction (LAEF), and tissue velocities (a', Ar) were compared between groups. Post-RFCA changes in these parameters were also assessed at 1, 3, and 6 months.
RESULTS
Pre-RFCA, PAF patients demonstrated larger LA dimensions and volumes with reduced LAEF and tissue velocities compared to controls. Post-RFCA, there was a significant improvement in LAEF and left ventricular ejection fraction at 1, 3, and 6 months, with the most pronounced changes observed at 6 months. LA dimensions increased initially but then decreased from 1 to 6 months post-RFCA. Notably, strain rate (SRS, SRE, SRA) measurements in various LA segments improved progressively, with the most significant enhancements at 6 months, suggesting improved atrial mechanics.
CONCLUSION
The application of 2D-STI and RT-3DE provides a quantitative means to evaluate the structural and functional changes in the LA of PAF patients following RFCA. The progressive improvements in LA dimensions, volumes, and strain measurements up to 6-month post-RFCA indicate the potential of these techniques in monitoring treatment efficacy and patient recovery.
INTRODUCTION
The aim of this study was to evaluate the utility of 2D-STI and real-time three-dimensional echocardiography (RT-3DE) in assessing changes in left atrial (LA) structure and function in patients with paroxysmal atrial fibrillation (PAF) post-radiofrequency catheter ablation (RFCA).
METHODS
A retrospective analysis was conducted on 44 PAF patients who underwent RFCA at BA Hospital from March 2022 to March 2023. An age- and gender-matched control group of 32 healthy individuals was also included. Comprehensive echocardiographic parameters including LA dimensions (LAAPD, LALRD), volumes (LAVmin, LAVmax), ejection fraction (LAEF), and tissue velocities (a', Ar) were compared between groups. Post-RFCA changes in these parameters were also assessed at 1, 3, and 6 months.
RESULTS
Pre-RFCA, PAF patients demonstrated larger LA dimensions and volumes with reduced LAEF and tissue velocities compared to controls. Post-RFCA, there was a significant improvement in LAEF and left ventricular ejection fraction at 1, 3, and 6 months, with the most pronounced changes observed at 6 months. LA dimensions increased initially but then decreased from 1 to 6 months post-RFCA. Notably, strain rate (SRS, SRE, SRA) measurements in various LA segments improved progressively, with the most significant enhancements at 6 months, suggesting improved atrial mechanics.
CONCLUSION
The application of 2D-STI and RT-3DE provides a quantitative means to evaluate the structural and functional changes in the LA of PAF patients following RFCA. The progressive improvements in LA dimensions, volumes, and strain measurements up to 6-month post-RFCA indicate the potential of these techniques in monitoring treatment efficacy and patient recovery.
引言
本研究的目的是评估二维应变成像（2D-STI）和实时三维超声心动图（RT-3DE）在评估阵发性心房颤动（PAF）患者射频导管消融（RFCA）术后左心房（LA）结构和功能变化中的作用。
方法
对2022年3月至2023年3月在BA医院接受RFCA的44例PAF患者进行回顾性分析。还纳入了32名年龄和性别匹配的健康个体作为对照组。比较两组之间包括LA直径（LAAPD、LALRD）、容积（LAVmin、LAVmax）、射血分数（LAEF）和组织速度（a'、Ar）在内的综合超声心动图参数。还在术后1个月、3个月和6个月评估这些参数的变化。
结果
与对照组相比，PAF患者在RFCA术前表现出更大的LA直径和容积，LAEF和组织速度降低。RFCA术后，在1个月、3个月和6个月时LAEF和左心室射血分数有显著改善，在6个月时变化最为明显。LA直径最初增加，但在RFCA术后1至6个月逐渐减小。值得注意的是，各个LA节段的应变率（SRS、SRE、SRA）测量值逐渐改善，在6个月时改善最为显著，提示心房力学改善。
结论
2D-STI和RT-3DE的应用提供了一种定量方法来评估PAF患者RFCA术后LA的结构和功能变化。RFCA术后长达6个月时LA直径、容积和应变测量值的逐渐改善表明这些技术在监测治疗效果和患者恢复方面的潜力。
引言
本研究的目的是评估二维应变成像（2D-STI）和实时三维超声心动图（RT-3DE）在评估阵发性心房颤动（PAF）患者射频导管消融（RFCA）术后左心房（LA）结构和功能变化中的作用。
方法
对2022年3月至2023年3月在BA医院接受RFCA的44例PAF患者进行回顾性分析。还纳入了32名年龄和性别匹配的健康个体作为对照组。比较两组之间包括LA直径（LAAPD、LALRD）、容积（LAVmin、LAVmax）、射血分数（LAEF）和组织速度（a'、Ar）在内的综合超声心动图参数。还在术后1个月、3个月和6个月评估这些参数的变化。
结果
与对照组相比，PAF患者在RFCA术前表现出更大的LA直径和容积，LAEF和组织速度降低。RFCA术后，在1个月、3个月和6个月时LAEF和左心室射血分数有显著改善，在6个月时变化最为明显。LA直径最初增加，但在RFCA术后1至6个月逐渐减小。值得注意的是，各个LA节段的应变率（SRS、SRE、SRA）测量值逐渐改善，在6个月时改善最为显著，提示心房力学改善。
结论
2D-STI和RT-3DE的应用提供了一种定量方法来评估PAF患者RFCA术后LA的结构和功能变化。RFCA术后长达6个月时LA直径、容积和应变测量值的逐渐改善表明这些技术在监测治疗效果和患者恢复方面的潜力。
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