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组织工程学的进展:生物打印技术、支架和生物墨水综述

Advancements in Tissue Engineering: A Review of Bioprinting Techniques, Scaffolds, and Bioinks.

作者信息

Zoghi Shervin

机构信息

School of Medicine, University of California, Davis, Sacramento, CA, USA.

出版信息

Biomed Eng Comput Biol. 2024 Oct 1;15:11795972241288099. doi: 10.1177/11795972241288099. eCollection 2024.

Abstract

Tissue engineering is a multidisciplinary field that uses biomaterials to restore tissue function and assist with drug development. Over the last decade, the fabrication of three-dimensional (3D) multifunctional scaffolds has become commonplace in tissue engineering and regenerative medicine. Thanks to the development of 3D bioprinting technologies, these scaffolds more accurately recapitulate in vivo conditions and provide the support structure necessary for microenvironments conducive to cell growth and function. The purpose of this review is to provide a background on the leading 3D bioprinting methods and bioink selections for tissue engineering applications, with a specific focus on the growing field of developing multifunctional bioinks and possible future applications.

摘要

组织工程是一个多学科领域,它利用生物材料来恢复组织功能并协助药物开发。在过去十年中,三维(3D)多功能支架的制造在组织工程和再生医学中已变得司空见惯。由于3D生物打印技术的发展,这些支架能更准确地模拟体内条件,并为有利于细胞生长和功能的微环境提供必要的支撑结构。本综述的目的是提供有关用于组织工程应用的主要3D生物打印方法和生物墨水选择的背景知识,特别关注不断发展的多功能生物墨水领域以及可能的未来应用。

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