鼻腔鼻窦错构瘤。
Sinonasal Hamartomas.
机构信息
Department of Pathology and Laboratory Medicine, Sinai Health System, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. Electronic address: https://twitter.com/ElanHahn.
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Laboratory Medicine Program, University Health Network, Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada.
出版信息
Surg Pathol Clin. 2024 Dec;17(4):577-585. doi: 10.1016/j.path.2024.07.001. Epub 2024 Aug 17.
A variety of hamartomatous lesions have been described in the sinonasal tract. These include respiratory epithelial adenomatoid hamartoma (REAH), seromucinous hamartoma (SH), and nasal chondromesenchymal hamartoma (NCMH). REAH and SH, demonstrate significant morphologic overlap with each other and with reactive conditions, while also being described to develop in association with other distinct tumors entities. NCMH affects a specific patient population with a specific molecular driver. The hamartomatous/neoplastic nature of REAH and SH are a topic of debate. There are emerging sinonasal hamartomatous entities that appear related to REAH and SH.
在鼻-鼻窦内已描述了多种错构瘤性病变。这些病变包括呼吸上皮腺腺瘤样错构瘤（REAH）、黏液-浆液性错构瘤（SH）和鼻软骨-间叶性错构瘤（NCMH）。REAH 和 SH 在形态上彼此之间以及与反应性病变之间存在显著的重叠，并且还被描述为与其他不同的肿瘤实体相关联而发生。NCMH 影响具有特定分子驱动因素的特定患者人群。REAH 和 SH 的错构瘤/肿瘤性质是一个有争议的话题。现在出现了一些与 REAH 和 SH 相关的新的鼻-鼻窦错构瘤性病变。
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