Wearable Aptasensors.

This Perspective explores the revolutionary advances in wearable aptasensor (WA) technology, which combines wearable devices and aptamer-based detection systems for personalized, real-time health monitoring. The devices leverage the specificity and sensitivity of aptamers to target specific molecules, offering broad applications from continuous glucose tracking to early diagnosis of diseases. The integration of data analytics and artificial intelligence (AI) allows early risk prediction and guides preventive health measures. While challenges in miniaturization, power efficiency, and data security persist, these devices hold significant potential to democratize healthcare and reshape patient-doctor interactions.