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评估家庭中未使用药物的流行情况及相关因素:基于社区的横断面研究。

Assessing the prevalence of unused medicines at home and associated factors: a community-based cross-sectional study.

机构信息

Department of Pharmaceutical Chemistry, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Pharmaceutical Sciences, Pharmaceutical Quality Assurance and Regulatory Affairs, University of Gondar, Gondar, Ethiopia.

出版信息

BMC Public Health. 2024 Nov 27;24(1):3307. doi: 10.1186/s12889-024-20847-5.

Abstract

BACKGROUND

Prescriptions come with extensive instructions on taking medicines but provide little information about the burden of unused medicines. This issue centers around the vast quantities of unused medications accumulated in households. The study aimed to assess the prevalence of unused medicines and associated factors in Gondar City.

METHOD

The study was conducted through a community-based cross-sectional survey in Gondar City from July 30 to August 30, 2023. The data was collected using the Kobo toolbox, exported into an Excel sheet, and then analyzed using SPSS version 27 software. Both multivariate and bivariate binary logistic regressions were performed in the data analysis. A p-value of 0.05 with a 95% confidence interval was used to determine statistical significance.

RESULT

The study interviewed 786 participants, with a 92.8% response rate. 55% of the 786 households surveyed kept unused medications at home, most commonly antibiotics (37%), antipyretics (17.6%), and analgesics (15%). Factors associated with having unused medicines at home included not receiving medication information (AOR = 2.327, 95% CI: 1.535, 3.527), having a chronic disease (AOR = 5.897, 95% CI: 3.667, 9.484), having health insurance coverage (AOR = 1.456, 95% CI: 1.036, 2.047), self-medicating with NSAIDs (AOR = 2.018, 95% CI: 1.396, 2.919), and poor disposal practices (AOR = 3.613, 95% CI: 2.546, 5.127).

CONCLUSION

The study found a considerable high prevalence of unused medications in Gondar City due to factors like lack of medication education, chronic conditions, insurance coverage, self-medication, and poor disposal practices. To address this, public education programs and safe disposal guidelines should be implemented to promote safer practices.

摘要

背景

处方提供了关于用药的详细说明,但几乎没有提供关于未使用药物负担的信息。这一问题主要集中在家庭中积累的大量未使用药物上。本研究旨在评估贡德尔市未使用药物的流行情况和相关因素。

方法

本研究于 2023 年 7 月 30 日至 8 月 30 日在贡德尔市进行了一项基于社区的横断面调查。使用 Kobo 工具包收集数据,将数据导出到 Excel 表格中,然后使用 SPSS 版本 27 软件进行分析。在数据分析中进行了多变量和双变量二元逻辑回归。使用 95%置信区间和 0.05 的 p 值来确定统计学意义。

结果

本研究共采访了 786 名参与者,响应率为 92.8%。在所调查的 786 户家庭中,有 55%的家庭家中存放有未使用的药物,最常见的是抗生素(37%)、解热药(17.6%)和镇痛药(15%)。与家中有未使用药物相关的因素包括未收到药物信息(AOR=2.327,95%CI:1.535,3.527)、患有慢性病(AOR=5.897,95%CI:3.667,9.484)、有健康保险(AOR=1.456,95%CI:1.036,2.047)、自行使用非甾体抗炎药(AOR=2.018,95%CI:1.396,2.919)和不良处置做法(AOR=3.613,95%CI:2.546,5.127)。

结论

本研究发现,由于缺乏药物教育、慢性病、保险覆盖、自我用药和不良处置做法等因素,贡德尔市未使用药物的流行率相当高。为了解决这一问题,应实施公众教育计划和安全处置指南,以促进更安全的做法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d958/11603730/5730c375e30a/12889_2024_20847_Fig1_HTML.jpg

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