Suppr超能文献

结合治疗性蛋白质作为治疗引发癌症发展的细菌的一种方法。

Conjugated therapeutic proteins as a treatment for bacteria which trigger cancer development.

作者信息

Halawa Mohamed, Newman Precious M, Aderibigbe Tope, Carabetta Valerie J

机构信息

Department of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA.

出版信息

iScience. 2024 Sep 26;27(10):111029. doi: 10.1016/j.isci.2024.111029. eCollection 2024 Oct 18.

Abstract

In recent years, an increasing amount of research has focused on the intricate and complex correlation between bacterial infections and the development of cancer. Some studies even identified specific bacterial species as potential culprits in the initiation of carcinogenesis, which generated a great deal of interest in the creation of innovative therapeutic strategies aimed at addressing both the infection and the subsequent risk of cancer. Among these strategies, there has been a recent emergence of the use of conjugated therapeutic proteins, which represent a highly promising avenue in the field of cancer therapeutics. These proteins offer a dual-targeting approach that seeks to effectively combat both the bacterial infection and the resulting malignancies that may arise because of such infections. This review delves into the landscape of conjugated therapeutic proteins that have been intricately designed with the purpose of specifically targeting bacteria that have been implicated in the induction of cancer.

摘要

近年来,越来越多的研究聚焦于细菌感染与癌症发展之间复杂且微妙的关联。一些研究甚至确定了特定的细菌种类是致癌起始的潜在元凶,这引发了人们对制定创新治疗策略的浓厚兴趣,这些策略旨在解决感染问题以及后续的癌症风险。在这些策略中,最近出现了使用偶联治疗性蛋白质的方法,这在癌症治疗领域是一条极具前景的途径。这些蛋白质提供了一种双靶点方法,旨在有效对抗细菌感染以及因这种感染可能引发的恶性肿瘤。本综述深入探讨了经过精心设计的偶联治疗性蛋白质的情况,其目的是专门靶向那些与癌症诱导有关的细菌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f1b/11615139/69e454c9e37a/fx1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验