Xia Qin, Peng Qianwen, Chen Hefeng, Zhang Weixia
Department of Pharmacy, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
J Multidiscip Healthc. 2024 Dec 3;17:5715-5723. doi: 10.2147/JMDH.S494004. eCollection 2024.
The comorbidity of coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) presents significant challenges in clinical management, particularly regarding glycemic control. The clinical management of CAD complicated by T2DM requires coordinated glycemic control, as poor management can exacerbate cardiovascular risks and increase morbidity and mortality. While endocrinologists traditionally manage diabetes, cardiologists are increasingly involved due to the cardiovascular risks associated with poor glycemic control. This study explores the current practices of glycemic management by cardiologists and endocrinologists in patients with CAD and T2DM, focusing on treatment intensification in a Chinese hospital setting.
This cross-sectional study included 1,074 hospitalized patients with both CAD and T2DM, admitted to the Cardiology Department of Ruijin Hospital between January 2021 and December 2023. Data were retrospectively collected from electronic medical records, including demographic information, clinical characteristics, and treatment interventions. Patients were stratified by year, and differences in treatment strategies between cardiologists and endocrinologists were analyzed. Glycemic control was assessed using HbA1c levels, with treatment intensification defined by any adjustment in antidiabetic therapy and consideration for comprehensive cardiovascular risk factors.
Endocrinologists were significantly more likely to initiate treatment intensification, especially in cases of severe hyperglycemia (HbA1c ≥9.0%), while cardiologists' role in glycemic management was limited, with a preference for outpatient endocrinology referrals over in-hospital adjustments. Despite improvements in glycemic control, the percentage of patients achieving comprehensive cardiovascular risk management targets remained low.
This study underscored the distinct yet complementary roles of cardiologists and endocrinologists in managing glycemic control among patients with CAD and T2DM, noting endocrinologists' more active involvement in treatment intensification. Future integrated care models should harness the unique expertise of both specialties to optimize patient outcomes, better address glycemic control needs, and enhance overall cardiovascular risk management in this high-risk patient population.
冠状动脉疾病(CAD)与2型糖尿病(T2DM)的合并存在给临床管理带来了重大挑战,尤其是在血糖控制方面。CAD合并T2DM的临床管理需要协调血糖控制,因为管理不善会加剧心血管风险并增加发病率和死亡率。虽然传统上由内分泌科医生管理糖尿病,但由于血糖控制不佳会带来心血管风险,心脏病专家也越来越多地参与其中。本研究探讨了心脏病专家和内分泌科医生对CAD合并T2DM患者进行血糖管理的当前做法,重点关注中国一家医院环境下的治疗强化情况。
这项横断面研究纳入了2021年1月至2023年12月期间在瑞金医院心内科住院的1074例CAD合并T2DM患者。数据从电子病历中回顾性收集,包括人口统计学信息、临床特征和治疗干预措施。患者按年份分层,分析心脏病专家和内分泌科医生之间治疗策略的差异。使用糖化血红蛋白(HbA1c)水平评估血糖控制情况,治疗强化定义为抗糖尿病治疗的任何调整以及对综合心血管危险因素的考虑。
内分泌科医生启动治疗强化的可能性显著更高,尤其是在严重高血糖(HbA1c≥9.0%)的情况下,而心脏病专家在血糖管理中的作用有限,更倾向于将患者转诊至门诊内分泌科而非在院内进行调整。尽管血糖控制有所改善,但实现综合心血管风险管理目标的患者比例仍然较低。
本研究强调了心脏病专家和内分泌科医生在管理CAD合并T2DM患者血糖控制方面的不同但互补的作用,指出内分泌科医生在治疗强化方面的参与更为积极。未来的综合护理模式应利用两个专业的独特专业知识,以优化患者结局,更好地满足血糖控制需求,并加强对这一高危患者群体的整体心血管风险管理。