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伴有强迫性迟缓的强迫症患者的前囊切开术和伏隔核切开术:一例报告

Anterior capsulotomy and accumbensotomy of obsessive-compulsive disorder with obsessional slowness: a case report.

作者信息

Lai Rui, Pang Xiao, Ming Yang, He Haiping, Xiong Yu, You Jian, Chen Ligang, Gong Feilong

机构信息

Department of Neurosurgery, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Neurosurgery Clinical Medical Research Center of Sichuan Province, Luzhou, Sichuan, China.

出版信息

Front Psychiatry. 2024 Nov 25;15:1498046. doi: 10.3389/fpsyt.2024.1498046. eCollection 2024.

Abstract

UNLABELLED

Obsessional slowness (OS) is characterized by a syndrome of extreme slowness in doing ordinary, day-to-day activities. Several scholars regarded OS as secondary to obsessive compulsive disorder (OCD). Therefore, it is commonly thought to be the consequence of extensive rituals and has been paid minimal attention in its own right. A combination of behavior therapy and aromatherapy are recommended for treatment of this condition. However, the outcome is often frustrating. Reports of surgical management for OS are limited.

PATIENT CONCERNS

She had symptoms characterized by repeated checking and progressive slowness in self-care behavior.

DIAGNOSIS

At the age of 19, the patient had the first presentation. The patient was diagnosed with a case of OCD with obsessional slowness according to the International Classification of Diseases and Related Health Problems (ICD-10).

INTERVENTIONS

Considering the lack of a response to pharmacotherapy and cognitive behavioral therapy (CBT), we treated this case with anterior capsulotomy and accumbensotomy.

OUTCOMES

Moderate somnolence, urticaria, juvenile behavior, mild short-term memory impairment and slight nonsense were noted during the first postoperative days. At 10 months, the patient's OCD symptoms recovered nearly to her preoperative level. The OS symptom also had an obvious rebound at 10 months. Through comprehensive judgment, we decided to choose accumbensotomy. At 9 months after the accumbensotomy, the OCD symptoms started to rebound. Soon after, the OS symptoms also recurred. At the last timepoint of 30 months, the patient's OCD and OS symptoms had completely rebounded. This time, the patient and parents refused any treatment.

CONCLUSION

This case suggests that OCD with OS, as a special category, might not be suitable for stereotactic neurosurgery. Furthermore, multiple surgeries in this kind of OCD patient should be considered with as much caution as much as possible.

摘要

未标注

强迫性迟缓(OS)的特征是在进行日常普通活动时极度迟缓的一种综合征。几位学者认为OS是强迫症(OCD)的继发症状。因此,人们普遍认为它是广泛仪式行为的结果,自身很少受到关注。推荐行为疗法和芳香疗法联合治疗这种病症。然而,结果往往令人沮丧。关于OS手术治疗的报道有限。

患者情况

她有反复检查和自我护理行为逐渐迟缓的症状。

诊断

患者19岁首次就诊。根据《国际疾病分类及相关健康问题》(ICD - 10),该患者被诊断为伴有强迫性迟缓的强迫症病例。

干预措施

考虑到药物治疗和认知行为疗法(CBT)均无反应,我们对该病例采用了前扣带回切开术和伏隔核切开术进行治疗。

结果

术后最初几天出现中度嗜睡、荨麻疹、幼稚行为、轻度短期记忆障碍和轻微胡言乱语。10个月时,患者的强迫症症状几乎恢复到术前水平。强迫性迟缓症状在10个月时也明显反弹。综合判断后,我们决定选择伏隔核切开术。伏隔核切开术后9个月,强迫症症状开始反弹。不久后,强迫性迟缓症状也复发。在30个月的最后观察点,患者的强迫症和强迫性迟缓症状完全反弹。此时,患者及其父母拒绝任何治疗。

结论

该病例表明,伴有强迫性迟缓的强迫症作为一种特殊类型,可能不适合立体定向神经外科手术。此外,对于这类强迫症患者进行多次手术应尽可能谨慎考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41b4/11625788/9e6c9e633b19/fpsyt-15-1498046-g001.jpg

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