Suppr超能文献

特应性皮炎:诊断与治疗综述

Atopic Dermatitis: A Review of Diagnosis and Treatment.

作者信息

Jeskey Jack, Kurien Christine, Blunk Henry, Sehmi Kiran, Areti Sathya, Nguyen Delena, Hostoffer Robert

机构信息

Department of Pulmonary & Critical Care, Allergy and Immunology Division, Case Western Reserve University/University Hospitals Cleveland Medical Center Program, Cleveland, OH.

出版信息

J Pediatr Pharmacol Ther. 2024 Dec;29(6):587-603. doi: 10.5863/1551-6776-29.6.587. Epub 2024 Dec 9.

Abstract

Atopic dermatitis, more commonly known as atopic eczema, is a chronic, relapsing inflammatory skin disorder characterized by dry skin, localized erythematous rash, and intense pruritus. The clinical manifestations are variable and age dependent. As one of the most common skin disorders globally, atopic dermatitis poses a significant clinical and economic burden on affected patients. Individual treatment strategies are imperative in improving patient outcomes and reducing these burdens. Recent advances in understanding the genetic, immunologic, and environmental factors influencing atopic dermatitis have opened avenues for novel treatment modalities. This article highlights the clinical presentation, pathophysiology, diagnosis criteria, as well as current recommendations on treatment of atopic dermatitis.

摘要

特应性皮炎,更常见的名称是特应性湿疹,是一种慢性复发性炎症性皮肤病,其特征为皮肤干燥、局限性红斑疹和剧烈瘙痒。临床表现多样且与年龄有关。作为全球最常见的皮肤疾病之一,特应性皮炎给受影响的患者带来了重大的临床和经济负担。个体化治疗策略对于改善患者预后和减轻这些负担至关重要。在理解影响特应性皮炎的遗传、免疫和环境因素方面的最新进展为新型治疗方式开辟了道路。本文重点介绍特应性皮炎的临床表现、病理生理学、诊断标准以及当前的治疗建议。

相似文献

1
Atopic Dermatitis: A Review of Diagnosis and Treatment.
J Pediatr Pharmacol Ther. 2024 Dec;29(6):587-603. doi: 10.5863/1551-6776-29.6.587. Epub 2024 Dec 9.
2
Clinical Presentation of Atopic Dermatitis.
Adv Exp Med Biol. 2017;1027:39-46. doi: 10.1007/978-3-319-64804-0_4.
4
Innovation in Atopic Dermatitis: From Pathogenesis to Treatment.
Actas Dermosifiliogr (Engl Ed). 2020 Apr;111(3):205-221. doi: 10.1016/j.ad.2019.11.002. Epub 2020 Jan 20.
5
Induction, treatment and prevention of eczema vaccinatum in atopic dermatitis mouse models.
Vaccine. 2017 Jul 24;35(33):4245-4254. doi: 10.1016/j.vaccine.2017.06.014. Epub 2017 Jun 20.
6
Abrocitinib, tralokinumab and upadacitinib for treating moderate-to-severe atopic dermatitis.
Health Technol Assess. 2024 Jan;28(4):1-113. doi: 10.3310/LEXB9006.
8
Expert opinion on management of moderate-to-severe atopic dermatitis in Qatar.
J Dermatolog Treat. 2023 Dec;34(1):2251622. doi: 10.1080/09546634.2023.2251622.
9
Management of Severe Atopic Dermatitis in Pediatric Patients.
J Allergy Clin Immunol Pract. 2021 Apr;9(4):1462-1471. doi: 10.1016/j.jaip.2021.02.017.
10
Biologics and Small Molecule Agents in Allergic and Immunologic Skin Diseases.
Curr Allergy Asthma Rep. 2018 Aug 31;18(10):55. doi: 10.1007/s11882-018-0804-8.

引用本文的文献

1
2
Chitosan Nanoparticles Loaded with Polyphenols for Cosmeceutical Applications: A State-of-the-Art Review.
Pharmaceutics. 2025 Aug 18;17(8):1068. doi: 10.3390/pharmaceutics17081068.
3
Atopic Dermatitis Management: from Conventional Therapies to Biomarker-Driven Treatment Approaches.
Biomol Ther (Seoul). 2025 Sep 1;33(5):813-829. doi: 10.4062/biomolther.2025.081. Epub 2025 Aug 19.

本文引用的文献

1
Bathing in Atopic Dermatitis in Pediatric Age: Why, How and When.
Pediatr Rep. 2024 Jan 8;16(1):57-68. doi: 10.3390/pediatric16010006.
3
Guidelines of care for the management of atopic dermatitis in adults with phototherapy and systemic therapies.
J Am Acad Dermatol. 2024 Feb;90(2):e43-e56. doi: 10.1016/j.jaad.2023.08.102. Epub 2023 Nov 7.
5
The long-term safety of topical corticosteroids in atopic dermatitis: A systematic review.
Skin Health Dis. 2023 Aug 16;3(5):e268. doi: 10.1002/ski2.268. eCollection 2023 Oct.
6
Systemic treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials.
J Allergy Clin Immunol. 2023 Dec;152(6):1470-1492. doi: 10.1016/j.jaci.2023.08.029. Epub 2023 Sep 9.
7
Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials.
J Allergy Clin Immunol. 2023 Dec;152(6):1493-1519. doi: 10.1016/j.jaci.2023.08.030. Epub 2023 Sep 9.
9
Atopic Dermatitis Yardstick update.
Ann Allergy Asthma Immunol. 2023 Jun;130(6):811-820. doi: 10.1016/j.anai.2023.03.010. Epub 2023 Mar 16.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验