希腊队列中与皮肤癌类型相关的皮肤癌知识、日晒情况、光防护行为及感知障碍：克里特岛的一项横断面研究
Skin Cancer Knowledge, Sun Exposure, Photoprotection Behavior, and Perceived Barriers Associated with Skin Cancer Types in a Greek Cohort: A Cross-Sectional Study on the Island of Crete.
作者信息
Koumaki Dimitra, Evangelou Georgios, Gregoriou Stamatios, Kouloumvakou Stamatoula, Manios Andreas, Katoulis Alexander, Zacharopoulos Georgios Vasileiou, Chernyshov Pavel Viktorovich, Papadakis Marios, Kassotakis Dimitrios, Manios Georgios A, Rovithi Evangelia, Zografaki Kyriaki, Doxastaki Aikaterini, Gkiaouraki Ioanna, Petrou Danae, Marazaki Faidra, Mylonakis Dimitrios, de Bree Eelco, Krasagakis Konstantinos
机构信息
Dermatology Department, University Hospital of Heraklion, 71110 Heraklion, Greece.
1st Department of Dermatology and Venereology, Andreas Sygros Hospital, National and Kapodistrian University of Athens, Medical School of Athens, I. Dragoumi 5, 16121 Athens, Greece.
出版信息
Cancers (Basel). 2024 Dec 18;16(24):4226. doi: 10.3390/cancers16244226.
BACKGORUND
This study aimed to explore the relationship between different types of skin cancer and factors such as sun exposure and photoprotection measures in a Greek cohort on the island of Crete.
METHODS
This cross-sectional observational study was conducted in the Dermatology Department of the University Hospital in Heraklion, Crete, between January 2019 and January 2024. The study population included consecutive patients diagnosed with basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma (MM), as well as healthy controls. The participants completed a self-reported questionnaire covering demographic and clinical data as well as questions about sun exposure and photoprotection habits.
RESULTS
A total of 265 skin cancer patients and 106 healthy controls participated in the study: 50.6% of the patients had basal cell carcinoma, 35.1% had squamous cell carcinoma, and 14.3% had malignant melanoma. The cohort comprised 41.5% females and 58.5% males, with a mean age of 73.2 years. As expected, the patients with skin cancer had a lighter skin phototype compared to the healthy controls ( < 0.01). They also reported greater occupational ( < 0.01) and leisure sun exposure ( < 0.01) and a higher median number of vacation weeks spent outdoors before the age of 18 ( = 0.030). Furthermore, the healthy controls were more likely to use sunscreen ( = 0.035) and preferred higher SPF (>50) when they did so ( < 0.01). The healthy controls also reported more frequent use of sunglasses ( < 0.01), brimmed hats ( < 0.01), and long-sleeved clothing ( < 0.01) compared to the skin cancer patients.
CONCLUSION
This is the first study to analyze sun exposure and photoprotection behaviors in patients with nonmelanoma skin cancer (NMSC) and malignant melanoma (MM) in Crete, revealing the key associations and underscoring the need for targeted prevention strategies.
背景
本研究旨在探讨希腊克里特岛队列中不同类型皮肤癌与日晒及光防护措施等因素之间的关系。
方法
本横断面观察性研究于2019年1月至2024年1月在克里特岛伊拉克利翁大学医院皮肤科进行。研究人群包括连续诊断为基底细胞癌（BCC）、鳞状细胞癌（SCC）和恶性黑色素瘤（MM）的患者以及健康对照。参与者完成了一份自我报告问卷，涵盖人口统计学和临床数据以及关于日晒和光防护习惯的问题。
结果
共有265名皮肤癌患者和106名健康对照参与了研究：50.6%的患者患有基底细胞癌，35.1%患有鳞状细胞癌，14.3%患有恶性黑色素瘤。该队列中女性占41.5%，男性占58.5%，平均年龄为73.2岁。正如预期的那样，与健康对照相比，皮肤癌患者的皮肤光类型更浅（<0.01）。他们还报告有更多的职业性日晒（<0.01）和休闲性日晒（<0.01），以及18岁之前在户外度过的假期周数中位数更高（=0.030）。此外，健康对照更有可能使用防晒霜（=0.035），并且在使用时更喜欢更高的防晒系数（>50）（<0.01）。与皮肤癌患者相比，健康对照还报告更频繁地使用太阳镜（<0.01）、宽边帽（<0.01）和长袖衣服（<0.01）。
结论
这是第一项分析克里特岛非黑色素瘤皮肤癌（NMSC）和恶性黑色素瘤（MM）患者日晒及光防护行为的研究，揭示了关键关联并强调了针对性预防策略的必要性。
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